Preventing coronary artery lesions in Kawasaki disease
A form of systemic vasculitis that affects mostly small and medium-sized vessels, Kawasaki disease (KD) is most commonly found in children under the age of 5 years old. Though its etiology is unknown, KD has been the most frequent acquired heart disease in developing countries. Its incidence has inc...
Main Author: | |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2017-06-01
|
Series: | Biomedical Journal |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2319417017300318 |
id |
doaj-7e92c6bb323a40e8963030d620ad5dde |
---|---|
record_format |
Article |
spelling |
doaj-7e92c6bb323a40e8963030d620ad5dde2021-04-02T11:28:07ZengElsevierBiomedical Journal2319-41702017-06-0140314114610.1016/j.bj.2017.04.002Preventing coronary artery lesions in Kawasaki diseaseHo-Chang Kuo0Kawasaki Disease Center, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, TaiwanA form of systemic vasculitis that affects mostly small and medium-sized vessels, Kawasaki disease (KD) is most commonly found in children under the age of 5 years old. Though its etiology is unknown, KD has been the most frequent acquired heart disease in developing countries. Its incidence has increased over recent decades in many centuries, including Japan, Korea, and China. The most severe complications of KD are coronary artery lesions (CAL), including dilation, fistula, aneurysm, arterial remodeling, stenosis, and occlusion. Aneurysm formation has been observed in 20–25% of KD patients that do not receive intravenous immunoglobulin (IVIG) treatment, and in 3–5% that do receive it. Coronary artery dilation has been found in about 30% of KD patients in the acute stage, although mostly in the transient form. Diminishing the occurrence and regression of CAL is a vital part of treating KD. In this review article, I demonstrate the clinical method to prevent CAL formation used at the Kawasaki Disease Center in Taiwan.http://www.sciencedirect.com/science/article/pii/S2319417017300318Kawasaki diseaseCoronary artery lesionPrevention |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ho-Chang Kuo |
spellingShingle |
Ho-Chang Kuo Preventing coronary artery lesions in Kawasaki disease Biomedical Journal Kawasaki disease Coronary artery lesion Prevention |
author_facet |
Ho-Chang Kuo |
author_sort |
Ho-Chang Kuo |
title |
Preventing coronary artery lesions in Kawasaki disease |
title_short |
Preventing coronary artery lesions in Kawasaki disease |
title_full |
Preventing coronary artery lesions in Kawasaki disease |
title_fullStr |
Preventing coronary artery lesions in Kawasaki disease |
title_full_unstemmed |
Preventing coronary artery lesions in Kawasaki disease |
title_sort |
preventing coronary artery lesions in kawasaki disease |
publisher |
Elsevier |
series |
Biomedical Journal |
issn |
2319-4170 |
publishDate |
2017-06-01 |
description |
A form of systemic vasculitis that affects mostly small and medium-sized vessels, Kawasaki disease (KD) is most commonly found in children under the age of 5 years old. Though its etiology is unknown, KD has been the most frequent acquired heart disease in developing countries. Its incidence has increased over recent decades in many centuries, including Japan, Korea, and China. The most severe complications of KD are coronary artery lesions (CAL), including dilation, fistula, aneurysm, arterial remodeling, stenosis, and occlusion. Aneurysm formation has been observed in 20–25% of KD patients that do not receive intravenous immunoglobulin (IVIG) treatment, and in 3–5% that do receive it. Coronary artery dilation has been found in about 30% of KD patients in the acute stage, although mostly in the transient form. Diminishing the occurrence and regression of CAL is a vital part of treating KD. In this review article, I demonstrate the clinical method to prevent CAL formation used at the Kawasaki Disease Center in Taiwan. |
topic |
Kawasaki disease Coronary artery lesion Prevention |
url |
http://www.sciencedirect.com/science/article/pii/S2319417017300318 |
work_keys_str_mv |
AT hochangkuo preventingcoronaryarterylesionsinkawasakidisease |
_version_ |
1724164703597363200 |