Association of Helicobacter pylori and Left Ventricular Ejection Fraction in Patients with Acute Myocardial Infarction
<p><strong>Background: </strong><em>Helicobacter pylori</em> (<em>H. pylori</em>) causes continuous inflammation of the stomach. It is suspected that <em>H. pylori</em> infection is associated with an inflammatory response in acute myocardial inf...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
DiscoverSys
2016-11-01
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| Series: | Bali Medical Journal |
| Subjects: | |
| Online Access: | https://balimedicaljournal.org/index.php/bmj/article/view/353 |
| Summary: | <p><strong>Background: </strong><em>Helicobacter pylori</em> (<em>H. pylori</em>) causes continuous inflammation of the stomach. It is suspected that <em>H. pylori</em> infection is associated with an inflammatory response in acute myocardial infarction (AMI). This research was aimed at analyzing the association of <em>Helicobacter</em> <em>pylori</em> infection and the degree of reduction in left ventricular ejection fraction (LVEF) in patients with AMI, the number of coronary heart disease (CHD) risk factors with <em>H. pylori</em> on AMI incident, and association of type of AMI and <em>H. pylori</em> on AMI incident. <strong>Method</strong><strong>: </strong>This is a prospective cohort study with observational-analytic method in AMI patients at ICCU of Prof. Dr. R. D. Kandou General Hospital Manado in 2015-2016. Data retrieval was done by filling out questionnaires, examination of blood samples, serology test to examine the presence of <em>H. pylori</em>, and echocardiography examination in patients with AMI. <strong>Results:</strong> Statistical analysis showed no significant association between <em>H. pylori</em> with the degree of reduction in LVEF in AMI patients (p=0.713), and the number of CHD risk factors (p=0.087). There was a significant association between H. pylori and types of IMA (p=0.017). There were more ST-Elevation Myocardial Infarction (STEMI) patients infected with <em>H. pylori</em>. <strong>Conclusion: </strong>There is no significant association between <em>H. pylori</em> infection and the degree of reduction in LVEF in AMI patients, and also the number of CHD risk factors. However, there is a significant association between AMI type and <em>H. pylori</em> on AMI, to wit there are more STEMI patients with <em>H. pylori</em> infections.</p> |
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| ISSN: | 2089-1180 2302-2914 |