Association of Helicobacter pylori and Left Ventricular Ejection Fraction in Patients with Acute Myocardial Infarction

• Main Authors: Starry Homenta Rampengan, Jimmy Posangi, Trina Ekawati Tallei, Suzanna Immanuel, Julius Lolombulan, Joedo Prihartono
• Format: Article
• Language: English
• Published: DiscoverSys 2016-11-01
• Series: Bali Medical Journal
• Subjects: acute myocardial infarction, helicobacter pylori, left ventricular ejection fraction
• Online Access: https://balimedicaljournal.org/index.php/bmj/article/view/353

<p><strong>Background: </strong><em>Helicobacter pylori</em> (<em>H. pylori</em>) causes continuous inflammation of the stomach. It is suspected that <em>H. pylori</em> infection is associated with an inflammatory response in acute myocardial infarction (AMI). This research was aimed at analyzing the association of <em>Helicobacter</em> <em>pylori</em> infection and the degree of reduction in left ventricular ejection fraction (LVEF) in patients with AMI, the number of coronary heart disease (CHD) risk factors with <em>H. pylori</em> on AMI incident, and association of type of AMI and <em>H. pylori</em> on AMI incident. <strong>Method</strong><strong>: </strong>This is a prospective cohort study with observational-analytic method in AMI patients at ICCU of Prof. Dr. R. D. Kandou General Hospital Manado in 2015-2016. Data retrieval was done by filling out questionnaires, examination of blood samples, serology test to examine the presence of <em>H. pylori</em>, and echocardiography examination in patients with AMI. <strong>Results:</strong> Statistical analysis showed no significant association between <em>H. pylori</em> with the degree of reduction in LVEF in AMI patients (p=0.713), and the number of CHD risk factors (p=0.087). There was a significant association between H. pylori and types of IMA (p=0.017). There were more ST-Elevation Myocardial Infarction (STEMI) patients infected with <em>H. pylori</em>. <strong>Conclusion: </strong>There is no significant association between <em>H. pylori</em> infection and the degree of reduction in LVEF in AMI patients, and also the number of CHD risk factors. However, there is a significant association between AMI type and <em>H. pylori</em> on AMI, to wit there are more STEMI patients with <em>H. pylori</em> infections.</p>