SPECT and PET Serve as Molecular Imaging Techniques and in Vivo Biomarkers for Brain Metastases

SPECT and PET Serve as Molecular Imaging Techniques and in Vivo Biomarkers for Brain Metastases

Nuclear medicine techniques (single photon emission computerized tomography, SPECT, and positron emission tomography, PET) represent molecular imaging tools, able to provide in vivo biomarkers of different diseases. To investigate brain tumours and metastases many different radiopharmaceuticals imag...

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Bibliographic Details
Main Authors: Barbara Palumbo, Tommaso Buresta, Susanna Nuvoli, Angela Spanu, Orazio Schillaci, Mario Luca Fravolini, Isabella Palumbo
Format: Article
Language:English
Published: MDPI AG 2014-06-01
Series:International Journal of Molecular Sciences
Subjects:
brain metastases
molecular imaging
PET
SPECT
MRI
fusion imaging
Online Access:http://www.mdpi.com/1422-0067/15/6/9878
Description
Summary:Nuclear medicine techniques (single photon emission computerized tomography, SPECT, and positron emission tomography, PET) represent molecular imaging tools, able to provide in vivo biomarkers of different diseases. To investigate brain tumours and metastases many different radiopharmaceuticals imaged by SPECT and PET can be used. In this review the main and most promising radiopharmaceuticals available to detect brain metastases are reported. Furthermore the diagnostic contribution of the combination of SPECT and PET data with radiological findings (magnetic resonance imaging, MRI) is discussed.
ISSN:1422-0067

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