Efficacy of Contact Needle Therapy for Chemotherapy-Induced Peripheral Neuropathy

Cancer chemotherapy-induced peripheral neuropathy (CIPN) often results in discontinuation of treatment with potentially useful anticancer drugs and may deteriorate the patient’s quality of life. This study investigated the effect of contact needle therapy (CNT) on CIPN caused by responsible chemothe...

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Main Authors: Keiko Ogawa, Masao Ogawa, Koji Nishijima, Masaki Tsuda, Genichi Nishimura
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2013/928129
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spelling doaj-7ea3d5866df04bde97a89dcf98dc695b2020-11-24T20:52:28ZengHindawi LimitedEvidence-Based Complementary and Alternative Medicine1741-427X1741-42882013-01-01201310.1155/2013/928129928129Efficacy of Contact Needle Therapy for Chemotherapy-Induced Peripheral NeuropathyKeiko Ogawa0Masao Ogawa1Koji Nishijima2Masaki Tsuda3Genichi Nishimura4Department of Otorhinolaryngology and Head and Neck Surgery, Clinic of Japanese Oriental (Kampo) Medicine, Kanazawa University Hospital, 13-1 Takaramachi, Kanazawa-City, Ishikawa 920-8641, JapanDepartment of Anesthesiology, Kanazawa Medical University Hospital, 1-1, Daigaku, Uchinada, Kahoku-gun, Ishikawa 920-0265, JapanDepartment of Surgery, Japanese Red Cross Kanazawa Hospital, Mima 2-251, Kanazawa 921-8162, JapanMukeido Acupuncture and Moxibustion Office, Niku 126-7, Horikawa, Koizumi-cho, Toyama 939-8081, JapanDepartment of Surgery, Japanese Red Cross Kanazawa Hospital, Mima 2-251, Kanazawa 921-8162, JapanCancer chemotherapy-induced peripheral neuropathy (CIPN) often results in discontinuation of treatment with potentially useful anticancer drugs and may deteriorate the patient’s quality of life. This study investigated the effect of contact needle therapy (CNT) on CIPN caused by responsible chemotherapeutic agents as taxanes and oxaliplatin. Six patients with CIPN were treated with CNT. The severity of CIPN was evaluated using the Common Terminology Criteria for Adverse Events (CTCAE) version 4 and FACT/GOG-Ntx before and after CNT. After the treatment, all of the patients showed some improvement. Four patients showed apparent improvement in breakthrough pain. One of the cases had difficulty in walking because of CIPN in lower extremities, but after 2 times of CNT, he could walk without pain and could continue the chemotherapy. Although its putative mechanisms remain elusive, CNT has strong potential as an adjunctive therapy in CIPN. Well-designed clinical trials with adequate sample size and power are necessary to confirm the findings of this study.http://dx.doi.org/10.1155/2013/928129
collection DOAJ
language English
format Article
sources DOAJ
author Keiko Ogawa
Masao Ogawa
Koji Nishijima
Masaki Tsuda
Genichi Nishimura
spellingShingle Keiko Ogawa
Masao Ogawa
Koji Nishijima
Masaki Tsuda
Genichi Nishimura
Efficacy of Contact Needle Therapy for Chemotherapy-Induced Peripheral Neuropathy
Evidence-Based Complementary and Alternative Medicine
author_facet Keiko Ogawa
Masao Ogawa
Koji Nishijima
Masaki Tsuda
Genichi Nishimura
author_sort Keiko Ogawa
title Efficacy of Contact Needle Therapy for Chemotherapy-Induced Peripheral Neuropathy
title_short Efficacy of Contact Needle Therapy for Chemotherapy-Induced Peripheral Neuropathy
title_full Efficacy of Contact Needle Therapy for Chemotherapy-Induced Peripheral Neuropathy
title_fullStr Efficacy of Contact Needle Therapy for Chemotherapy-Induced Peripheral Neuropathy
title_full_unstemmed Efficacy of Contact Needle Therapy for Chemotherapy-Induced Peripheral Neuropathy
title_sort efficacy of contact needle therapy for chemotherapy-induced peripheral neuropathy
publisher Hindawi Limited
series Evidence-Based Complementary and Alternative Medicine
issn 1741-427X
1741-4288
publishDate 2013-01-01
description Cancer chemotherapy-induced peripheral neuropathy (CIPN) often results in discontinuation of treatment with potentially useful anticancer drugs and may deteriorate the patient’s quality of life. This study investigated the effect of contact needle therapy (CNT) on CIPN caused by responsible chemotherapeutic agents as taxanes and oxaliplatin. Six patients with CIPN were treated with CNT. The severity of CIPN was evaluated using the Common Terminology Criteria for Adverse Events (CTCAE) version 4 and FACT/GOG-Ntx before and after CNT. After the treatment, all of the patients showed some improvement. Four patients showed apparent improvement in breakthrough pain. One of the cases had difficulty in walking because of CIPN in lower extremities, but after 2 times of CNT, he could walk without pain and could continue the chemotherapy. Although its putative mechanisms remain elusive, CNT has strong potential as an adjunctive therapy in CIPN. Well-designed clinical trials with adequate sample size and power are necessary to confirm the findings of this study.
url http://dx.doi.org/10.1155/2013/928129
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