CARBOHYDRATE METABOLISM DISTURBANCES: THERAPEUTIC POTENTIAL IN METABOLIC SYNDROME
The study was focused on dibicor effects on carbohydrate metabolism (CM) and insulin resistance (IR) in patients with metabolic syndrome (MS), as well as the correlations between various CM parameters, chronic heart failure (CHF), and abdominal obesity (AO). In total, 61 patients aged 31–66 years ga...
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doaj-7ebb3f1ff521476584dde98a6b03fac52021-07-28T14:02:12Zrus«FIRMA «SILICEA» LLC Российский кардиологический журнал1560-40712618-76202009-04-010244481126CARBOHYDRATE METABOLISM DISTURBANCES: THERAPEUTIC POTENTIAL IN METABOLIC SYNDROMEI. V. Kryuchkova0A. S. Adamchik1Кубанский государственный медицинский университет, кафедра пропедевтики внутренних болезней, КраснодарКубанский государственный медицинский университет, кафедра пропедевтики внутренних болезней, КраснодарThe study was focused on dibicor effects on carbohydrate metabolism (CM) and insulin resistance (IR) in patients with metabolic syndrome (MS), as well as the correlations between various CM parameters, chronic heart failure (CHF), and abdominal obesity (AO). In total, 61 patients aged 31–66 years gave their informed consent to participate in the study, including 21,7% of men and 78,3% of women. The control group (n=30) received standard therapy only, while the main group (n=30) also received dibicor. All participants underwent anthropometry, blood pressure and IR measurement, lipid and carbohydrate metabolism assessment. Twelve-month dibicor therapy was associated with improved CM and reduced IR. Functional class (FC) of CHF directly correlated with CM disturbance severity, while AO correlated with fasting and glucose tolerance test levels of plasma glucose. In MS and CHF, dibicor improved CM, reduced IR, and therefore, facilitated the CHF FC reduction.https://russjcardiol.elpub.ru/jour/article/view/1336metabolic syndromechronic heart failurecarbohydrate metabolisminsulin resistancedibicor |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
I. V. Kryuchkova A. S. Adamchik |
spellingShingle |
I. V. Kryuchkova A. S. Adamchik CARBOHYDRATE METABOLISM DISTURBANCES: THERAPEUTIC POTENTIAL IN METABOLIC SYNDROME Российский кардиологический журнал metabolic syndrome chronic heart failure carbohydrate metabolism insulin resistance dibicor |
author_facet |
I. V. Kryuchkova A. S. Adamchik |
author_sort |
I. V. Kryuchkova |
title |
CARBOHYDRATE METABOLISM DISTURBANCES: THERAPEUTIC POTENTIAL IN METABOLIC SYNDROME |
title_short |
CARBOHYDRATE METABOLISM DISTURBANCES: THERAPEUTIC POTENTIAL IN METABOLIC SYNDROME |
title_full |
CARBOHYDRATE METABOLISM DISTURBANCES: THERAPEUTIC POTENTIAL IN METABOLIC SYNDROME |
title_fullStr |
CARBOHYDRATE METABOLISM DISTURBANCES: THERAPEUTIC POTENTIAL IN METABOLIC SYNDROME |
title_full_unstemmed |
CARBOHYDRATE METABOLISM DISTURBANCES: THERAPEUTIC POTENTIAL IN METABOLIC SYNDROME |
title_sort |
carbohydrate metabolism disturbances: therapeutic potential in metabolic syndrome |
publisher |
«FIRMA «SILICEA» LLC |
series |
Российский кардиологический журнал |
issn |
1560-4071 2618-7620 |
publishDate |
2009-04-01 |
description |
The study was focused on dibicor effects on carbohydrate metabolism (CM) and insulin resistance (IR) in patients with metabolic syndrome (MS), as well as the correlations between various CM parameters, chronic heart failure (CHF), and abdominal obesity (AO). In total, 61 patients aged 31–66 years gave their informed consent to participate in the study, including 21,7% of men and 78,3% of women. The control group (n=30) received standard therapy only, while the main group (n=30) also received dibicor. All participants underwent anthropometry, blood pressure and IR measurement, lipid and carbohydrate metabolism assessment. Twelve-month dibicor therapy was associated with improved CM and reduced IR. Functional class (FC) of CHF directly correlated with CM disturbance severity, while AO correlated with fasting and glucose tolerance test levels of plasma glucose. In MS and CHF, dibicor improved CM, reduced IR, and therefore, facilitated the CHF FC reduction. |
topic |
metabolic syndrome chronic heart failure carbohydrate metabolism insulin resistance dibicor |
url |
https://russjcardiol.elpub.ru/jour/article/view/1336 |
work_keys_str_mv |
AT ivkryuchkova carbohydratemetabolismdisturbancestherapeuticpotentialinmetabolicsyndrome AT asadamchik carbohydratemetabolismdisturbancestherapeuticpotentialinmetabolicsyndrome |
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1721269562726416384 |