Programming of neuroendocrine self in the thymus and its defect in the development of neuroendocrine autoimmunity

Programming of neuroendocrine self in the thymus and its defect in the development of neuroendocrine autoimmunity

For centuries after its first description by Galen, the thymus was considered as only a vestigial endocrine organ until the discovery in 1961 by Jacques FAP Miller of its essential role in the development of T (thymo-dependent) lymphocytes. A unique thymus first appeared in cartilaginous fishes some...

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Bibliographic Details
Main Authors: Vincent eGeenen, Gwennaëlle eBodart, Séverine eHenry, Hélène eMichaux, Olivier eDardenne, Chantal eCharlet-Renard, Henri eMartens, Didier eHober
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Neuroscience
Subjects:
Autoimmunity
Coxsackievirus Infections
Oxytocin
type 1 diabetes
AIRE
self-tolerance
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2013.00187/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnins.2013.00187/full

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