B7-H3 inhibits the IFN-γ-dependent cytotoxicity of Vγ9Vδ2 T cells against colon cancer cells

B7-H3 inhibits the IFN-γ-dependent cytotoxicity of Vγ9Vδ2 T cells against colon cancer cells

The immunoregulatory protein B7-H3, a member of the B7 family, has been confirmed to be highly expressed in colon cancer. However, the exact influence of B7-H3 on the features and antitumor ability of γδT cells in colon cancer remains unknown. In the present study, we investigated that the proportio...

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Bibliographic Details
Main Authors:	Huimin Lu, Tongguo Shi, Mingyuan Wang, Xiaomi Li, Yanzheng Gu, Xueguang Zhang, Guangbo Zhang, Weichang Chen
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2020-01-01
Series:	OncoImmunology
Subjects:	colon cancer γδt cells b7-h3 ifn-γ perforin/granzyme pathway
Online Access:	http://dx.doi.org/10.1080/2162402X.2020.1748991

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