Role of Thrombin in Central Nervous System Injury and Disease

Role of Thrombin in Central Nervous System Injury and Disease

Thrombin is a Na<sup>+</sup>-activated allosteric serine protease of the chymotrypsin family involved in coagulation, inflammation, cell protection, and apoptosis. Increasingly, the role of thrombin in the brain has been explored. Low concentrations of thrombin are neuroprotective, while...

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Bibliographic Details
Main Authors: Nathan A. Shlobin, Meirav Har-Even, Ze’ev Itsekson-Hayosh, Sagi Harnof, Chaim G. Pick
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Biomolecules
Subjects:
blood–brain barrier
glioblastoma
neurodegenerative diseases
neuroinflammation
protease-activated receptor
prothrombin
Online Access:https://www.mdpi.com/2218-273X/11/4/562

Internet

https://www.mdpi.com/2218-273X/11/4/562

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