Reduced Graphene Oxides: Influence of the Reduction Method on the Electrocatalytic Effect towards Nucleic Acid Oxidation
For the first time a critical analysis of the influence that four different graphene oxide reduction methods have on the electrochemical properties of the resulting reduced graphene oxides (RGOs) is reported. Starting from the same graphene oxide, chemical (CRGO), hydrothermal (hTRGO), electrochemic...
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doaj-7f1a8d9f92134370a8b33b0302fd69192020-11-24T22:50:03ZengMDPI AGNanomaterials2079-49912017-07-017716810.3390/nano7070168nano7070168Reduced Graphene Oxides: Influence of the Reduction Method on the Electrocatalytic Effect towards Nucleic Acid OxidationDaniela F. Báez0Helena Pardo1Ignacio Laborda2José F. Marco3Claudia Yáñez4Soledad Bollo5Centro de Investigación de Procesos Redox, CiPRex, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Sergio Livingstone 1007, Independencia, Santiago 8380492, ChileFacultad de Química, Universidad de la República de Uruguay, Avenida General Flores 2124, Montevideo 11800, UruguayFacultad de Química, Universidad de la República de Uruguay, Avenida General Flores 2124, Montevideo 11800, UruguayInstituto de Química Física Rocasolano, CSIC, calle Serrano 119, 28006 Madrid, SpainCentro de Investigación de Procesos Redox, CiPRex, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Sergio Livingstone 1007, Independencia, Santiago 8380492, ChileCentro de Investigación de Procesos Redox, CiPRex, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Sergio Livingstone 1007, Independencia, Santiago 8380492, ChileFor the first time a critical analysis of the influence that four different graphene oxide reduction methods have on the electrochemical properties of the resulting reduced graphene oxides (RGOs) is reported. Starting from the same graphene oxide, chemical (CRGO), hydrothermal (hTRGO), electrochemical (ERGO), and thermal (TRGO) reduced graphene oxide were produced. The materials were fully characterized and the topography and electroactivity of the resulting glassy carbon modified electrodes were also evaluated. An oligonucleotide molecule was used as a model of DNA electrochemical biosensing. The results allow for the conclusion that TRGO produced the RGOs with the best electrochemical performance for oligonucleotide electroanalysis. A clear shift in the guanine oxidation peak potential to lower values (~0.100 V) and an almost two-fold increase in the current intensity were observed compared with the other RGOs. The electrocatalytic effect has a multifactorial explanation because the TRGO was the material that presented a higher polydispersity and lower sheet size, thus exposing a larger quantity of defects to the electrode surface, which produces larger physical and electrochemical areas.https://www.mdpi.com/2079-4991/7/7/168graphenereduced graphene oxideglassy carbon electrodeSECMDNA oxidation |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Daniela F. Báez Helena Pardo Ignacio Laborda José F. Marco Claudia Yáñez Soledad Bollo |
spellingShingle |
Daniela F. Báez Helena Pardo Ignacio Laborda José F. Marco Claudia Yáñez Soledad Bollo Reduced Graphene Oxides: Influence of the Reduction Method on the Electrocatalytic Effect towards Nucleic Acid Oxidation Nanomaterials graphene reduced graphene oxide glassy carbon electrode SECM DNA oxidation |
author_facet |
Daniela F. Báez Helena Pardo Ignacio Laborda José F. Marco Claudia Yáñez Soledad Bollo |
author_sort |
Daniela F. Báez |
title |
Reduced Graphene Oxides: Influence of the Reduction Method on the Electrocatalytic Effect towards Nucleic Acid Oxidation |
title_short |
Reduced Graphene Oxides: Influence of the Reduction Method on the Electrocatalytic Effect towards Nucleic Acid Oxidation |
title_full |
Reduced Graphene Oxides: Influence of the Reduction Method on the Electrocatalytic Effect towards Nucleic Acid Oxidation |
title_fullStr |
Reduced Graphene Oxides: Influence of the Reduction Method on the Electrocatalytic Effect towards Nucleic Acid Oxidation |
title_full_unstemmed |
Reduced Graphene Oxides: Influence of the Reduction Method on the Electrocatalytic Effect towards Nucleic Acid Oxidation |
title_sort |
reduced graphene oxides: influence of the reduction method on the electrocatalytic effect towards nucleic acid oxidation |
publisher |
MDPI AG |
series |
Nanomaterials |
issn |
2079-4991 |
publishDate |
2017-07-01 |
description |
For the first time a critical analysis of the influence that four different graphene oxide reduction methods have on the electrochemical properties of the resulting reduced graphene oxides (RGOs) is reported. Starting from the same graphene oxide, chemical (CRGO), hydrothermal (hTRGO), electrochemical (ERGO), and thermal (TRGO) reduced graphene oxide were produced. The materials were fully characterized and the topography and electroactivity of the resulting glassy carbon modified electrodes were also evaluated. An oligonucleotide molecule was used as a model of DNA electrochemical biosensing. The results allow for the conclusion that TRGO produced the RGOs with the best electrochemical performance for oligonucleotide electroanalysis. A clear shift in the guanine oxidation peak potential to lower values (~0.100 V) and an almost two-fold increase in the current intensity were observed compared with the other RGOs. The electrocatalytic effect has a multifactorial explanation because the TRGO was the material that presented a higher polydispersity and lower sheet size, thus exposing a larger quantity of defects to the electrode surface, which produces larger physical and electrochemical areas. |
topic |
graphene reduced graphene oxide glassy carbon electrode SECM DNA oxidation |
url |
https://www.mdpi.com/2079-4991/7/7/168 |
work_keys_str_mv |
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