Multiplex Serum Protein Analysis Identifies Novel Biomarkers of Advanced Fibrosis in Patients with Chronic Liver Disease with the Potential to Improve Diagnostic Accuracy of Established Biomarkers.
Non-invasive markers of liver fibrosis are urgently required, especially for use in non-specialist settings. The aim of this study was to identify novel serum biomarkers of advanced fibrosis.We performed an unbiased screen of 120 serum analytes including cytokines, chemokines and proteases in 70 pat...
Main Authors: | Katharine M Irvine, Leesa F Wockner, Isabell Hoffmann, Leigh U Horsfall, Kevin J Fagan, Veonice Bijin, Bernett Lee, Andrew D Clouston, Guy Lampe, John E Connolly, Elizabeth E Powell |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5115865?pdf=render |
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