Effects of elaidic acid on lipid metabolism in HepG2 cells, investigated by an integrated approach of lipidomics, transcriptomics and proteomics.

Effects of elaidic acid on lipid metabolism in HepG2 cells, investigated by an integrated approach of lipidomics, transcriptomics and proteomics.

Trans fatty acid consumption in the human diet can cause adverse health effects, such as cardiovascular disease, which is associated with higher total cholesterol, a higher low density lipoprotein-cholesterol level and a decreased high density lipoprotein-cholesterol level. The aim of the study was...

Full description

Bibliographic Details
Main Authors:	Lone Vendel Nielsen, Toke P Krogager, Clifford Young, Carla Ferreri, Chryssostomos Chatgilialoglu, Ole Nørregaard Jensen, Jan J Enghild
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2013-01-01
Series:	PLoS ONE
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24058537/?tool=EBI

Similar Items

Nutrition and Reproductive Health: Sperm versus Erythrocyte Lipidomic Profile and ω-3 Intake
by: Gabriela Ruth Mendeluk, et al.
Published: (2015-01-01)

Metabolism of methyl elaidate*
by: G.A. Dhopeshwarkar, et al.
Published: (1962-04-01)

Lipidomic data uncover extensive heterogeneity in phosphatidylcholine structural variants in HepG2 cells
by: Yolanda Chico, et al.
Published: (2019-12-01)

The n-10 Fatty Acids Family in the Lipidome of Human Prostatic Adenocarcinoma Cell Membranes and Extracellular Vesicles
by: Carla Ferreri, et al.
Published: (2020-04-01)

Free-Radical-Mediated Formation of Trans-Cardiolipin Isomers, Analytical Approaches for Lipidomics and Consequences of the Structural Organization of Membranes
by: Fabrizio Vetica, et al.
Published: (2020-08-01)

Membrane lipidome reorganization correlates with the fate of neuroblastoma cells supplemented with fatty acids.
by: Andrea Bolognesi, et al.
Published: (2013-01-01)

Elaidic acid (trans-9-octadecenoic acid)
by: Low, J.N, et al.
Published: (2005)

Membrane Lipidome Reorganization and Accumulation of Tissue DNA Lesions in Tumor-Bearing Mice: An Exploratory Study
by: Marios G. Krokidis, et al.
Published: (2019-04-01)

Effects of Elaidic Acid on HDL Cholesterol Uptake Capacity
by: Takuya Iino, et al.
Published: (2021-09-01)

Radiation-induced formation of purine lesions in single and double stranded DNA: Revised quantification
by: Michael A. Terzidis, et al.
Published: (2015-03-01)

Global Proteomics to Study Silica Nanoparticle-Induced Cytotoxicity and Its Mechanisms in HepG2 Cells
by: Sun Young Lee, et al.
Published: (2021-03-01)

Proteomics based identification of cell migration related proteins in HBV expressing HepG2 cells.
by: Huixing Feng, et al.
Published: (2014-01-01)

Continual proteomic divergence of HepG2 cells as a consequence of long-term spheroid culture
by: Andrea Antonio Ellero, et al.
Published: (2021-05-01)

Biomimetic chemistry on the protection of cis phospholipid from the thiyl radical isomerization by common antioxidants
by: Ioannis N. Lykakis, et al.
Published: (2015-02-01)

Transcriptome Analyses of the Anti-Proliferative Effects of 20(S)-Ginsenoside Rh2 on HepG2 Cells
by: Ji Zhang, et al.
Published: (2019-11-01)

RNA-sequencing analysis of HepG2 cells treated with atorvastatin.
by: Camilla Stormo, et al.
Published: (2014-01-01)

Transformation of HepG2 nascent lipoproteins by LCAT: modulation by HepG2 d > 1.235 g/ml fraction.
by: MR McCall, et al.
Published: (1993-01-01)

The Erythrocyte Membrane Lipidome of Healthy Dogs: Creating a Benchmark of Fatty Acid Distribution and Interval Values
by: Paraskevi Prasinou, et al.
Published: (2020-08-01)

Effects of nucleosides on the induction of apoptosis in HepG2 and Hep3B cells.
by: Che-Lin Chiu, et al.
Published: (2003)

A comparison of the metabolism of elaidic, oleic, palmitic, and stearic acids in the rat
by: Robert H. Coots
Published: (1964-07-01)

Membrane lipidomics: the reorganization of fatty acids as a biomarker of cell condition
by: Chatgilialoglu, Alexandros <1981>
Published: (2009)

The Two Faces of the Guanyl Radical: Molecular Context and Behavior
by: Chryssostomos Chatgilialoglu
Published: (2021-06-01)

Regulation of squalene epoxidase in HepG2 cells.
by: Y Hidaka, et al.
Published: (1990-11-01)

The Fatty Acid-Based Erythrocyte Membrane Lipidome in Dogs with Chronic Enteropathy
by: Paolo Emidio Crisi, et al.
Published: (2021-09-01)

Hexadecenoic Fatty Acid Isomers in Human Blood Lipids and Their Relevance for the Interpretation of Lipidomic Profiles.
by: Anna Sansone, et al.
Published: (2016-01-01)

Proteomic Investigation to Identify Anticancer Targets of Nemopilema nomurai Jellyfish Venom in Human Hepatocarcinoma HepG2 Cells
by: Indu Choudhary, et al.
Published: (2018-05-01)

Kinetics of the elaidization’s reaction of oleic acid in the deodorization and/or physical refining of edible fats
by: M. León Camacho, et al.
Published: (2003-06-01)

Effects of Estrogen and Estrogen Receptors on Transcriptomes of HepG2 Cells: A Preliminary Study Using RNA Sequencing
by: Minqian Shen, et al.
Published: (2018-01-01)

Nevirapine induced mitochondrial dysfunction in HepG2 cells
by: Atchara Paemanee, et al.
Published: (2017-08-01)

Characterization of dengue virus entry into HepG2 cells
by: Suksanpaisan Lukkana, et al.
Published: (2009-02-01)

Characterization of mitochondrial iron uptake in HepG2 cells
by: DORA INÉS MAZARIEGOS, et al.
Published: (2006-01-01)

Effects of berberine and coptisine on hepatoma HepG2 cells
by: Feng I-chieh, et al.

Study On The Regulation Of Metabolism In HepG2 Cells By Astragalosides
by: Hsin-Yi Lo, et al.
Published: (2012)

Electrophoresis of HepG2 Cells: Experimental and Theoretical Modeling
by: Li-chia Yang, et al.
Published: (2005)

The effects of troglitazone and PMA on AMPK in HepG2 cells
by: Allen, Katherine
Published: (2016)

The Fatty Acid β-Oxidation Pathway is Activated by Leucine Deprivation in HepG2 Cells: A Comparative Proteomics Study
by: Guokai Yan, et al.
Published: (2017-05-01)

DNA and Proteomic Expression of Cervi parvum cornu Herbal-acupuncture Solution (CPC-HAS) in HepG2 carcinomar cells
by: Ryu Sung-hyun, et al.
Published: (2006-06-01)

Cationic liposomes induce cytotoxicity in HepG2 via regulation of lipid metabolism based on whole-transcriptome sequencing analysis
by: Ying Li, et al.
Published: (2018-07-01)

A proton magnetic resonance investigation of molecular motion in oleic acid and elaidic acid
by: Ware, Donald Robert
Published: (2011)

Isomerization of stable isotopically labeled elaidic acid to cis and trans monoenes by ruminal microbes
by: Julie M. Proell, et al.
Published: (2002-12-01)