Exploring the Management of Radiation Proctitis in Current Clinical Practice
Introduction: Radiation proctitis is radiation induced rectal mucositis, occurring as a consequence to radiation therapy of the pelvic organs for various pelvic region malignancies. The management of radiation proctitis is extremely challenging as no recommended guidelines are available and limi...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
JCDR Research and Publications Private Limited
2016-06-01
|
Series: | Journal of Clinical and Diagnostic Research |
Subjects: | |
Online Access: | https://jcdr.net/articles/PDF/7906/17524_CE[Ra1]_F(P)_PF1(ROAK)_PFA(AK)_PF2(PAG).pdf |
id |
doaj-7f247d53832d43f4b7db9a92584a7340 |
---|---|
record_format |
Article |
spelling |
doaj-7f247d53832d43f4b7db9a92584a73402020-11-25T03:20:08ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2016-06-01106XE01XE0610.7860/JCDR/2016/17524.7906Exploring the Management of Radiation Proctitis in Current Clinical PracticeNupur Bansal0Abhishek Soni1Paramjeet Kaur2Ashok Kumar Chauhan3Vivek Kaushal4Senior Resident, Department of Radiotherapy, Pt. B.D. Sharma PGIMS, Rohtak, India.Senior Resident, Department of Radiotherapy, Pt. B.D. Sharma PGIMS, Rohtak, India.Associate Professor, Department of Radiotherapy, Pt. B.D. Sharma PGIMS, Rohtak, India.Senior Professor, Department of Radiotherapy, Pt. B.D. Sharma PGIMS, Rohtak, India. Senior Professor, Department of Radiotherapy, Pt. B.D. Sharma PGIMS, Rohtak, India.Introduction: Radiation proctitis is radiation induced rectal mucositis, occurring as a consequence to radiation therapy of the pelvic organs for various pelvic region malignancies. The management of radiation proctitis is extremely challenging as no recommended guidelines are available and limited number of studies are there in the literature involving the various treatment options. Aim: The aim of the study is the in-depth review of published literature to see the role of various treatment modalities in the management of radiation proctitis. Materials and Methods: An integrative review was undertaken within PubMed, MEDLINE, PMC, GOOGLE SEARCH databases and articles published upto February 2015 were reviewed and analysed. A total of 54 studies were included. Results: Literature suggests that non surgical therapies are the first line of treatment and surgery is reserved for advanced or refractory cases. Endoscopic therapies form the mainstay of treatment in managing the patients of radiation proctitis. Argon plasma coagulation and laser therapies are preferred. Radiofrequency ablation, cryoablation and mesenchymal stem cell therapy are the upcoming modalities. Medical therapy can be tried alone or in conjunction to endoscopic therapies. In the resistant or refractory cases, surgery can be looked for in the form of diversion or resection with or without anastamosis. Conclusion: Though, a number of options are available, still a lot can be explored in this field to improve the morbidity in the patients and to confirm the superiority of one treatment over other. https://jcdr.net/articles/PDF/7906/17524_CE[Ra1]_F(P)_PF1(ROAK)_PFA(AK)_PF2(PAG).pdfendoscopicmedicalproctopathysteroidssurgery |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Nupur Bansal Abhishek Soni Paramjeet Kaur Ashok Kumar Chauhan Vivek Kaushal |
spellingShingle |
Nupur Bansal Abhishek Soni Paramjeet Kaur Ashok Kumar Chauhan Vivek Kaushal Exploring the Management of Radiation Proctitis in Current Clinical Practice Journal of Clinical and Diagnostic Research endoscopic medical proctopathy steroids surgery |
author_facet |
Nupur Bansal Abhishek Soni Paramjeet Kaur Ashok Kumar Chauhan Vivek Kaushal |
author_sort |
Nupur Bansal |
title |
Exploring the Management of Radiation Proctitis in Current Clinical Practice |
title_short |
Exploring the Management of Radiation Proctitis in Current Clinical Practice |
title_full |
Exploring the Management of Radiation Proctitis in Current Clinical Practice |
title_fullStr |
Exploring the Management of Radiation Proctitis in Current Clinical Practice |
title_full_unstemmed |
Exploring the Management of Radiation Proctitis in Current Clinical Practice |
title_sort |
exploring the management of radiation proctitis in current clinical practice |
publisher |
JCDR Research and Publications Private Limited |
series |
Journal of Clinical and Diagnostic Research |
issn |
2249-782X 0973-709X |
publishDate |
2016-06-01 |
description |
Introduction: Radiation proctitis is radiation induced rectal
mucositis, occurring as a consequence to radiation therapy of
the pelvic organs for various pelvic region malignancies. The
management of radiation proctitis is extremely challenging as
no recommended guidelines are available and limited number of
studies are there in the literature involving the various treatment
options.
Aim: The aim of the study is the in-depth review of published
literature to see the role of various treatment modalities in the
management of radiation proctitis.
Materials and Methods: An integrative review was undertaken
within PubMed, MEDLINE, PMC, GOOGLE SEARCH databases
and articles published upto February 2015 were reviewed and
analysed. A total of 54 studies were included.
Results: Literature suggests that non surgical therapies are
the first line of treatment and surgery is reserved for advanced
or refractory cases. Endoscopic therapies form the mainstay
of treatment in managing the patients of radiation proctitis.
Argon plasma coagulation and laser therapies are preferred.
Radiofrequency ablation, cryoablation and mesenchymal stem
cell therapy are the upcoming modalities. Medical therapy can
be tried alone or in conjunction to endoscopic therapies. In the
resistant or refractory cases, surgery can be looked for in the
form of diversion or resection with or without anastamosis.
Conclusion: Though, a number of options are available, still a
lot can be explored in this field to improve the morbidity in the
patients and to confirm the superiority of one treatment over
other. |
topic |
endoscopic medical proctopathy steroids surgery |
url |
https://jcdr.net/articles/PDF/7906/17524_CE[Ra1]_F(P)_PF1(ROAK)_PFA(AK)_PF2(PAG).pdf |
work_keys_str_mv |
AT nupurbansal exploringthemanagementofradiationproctitisincurrentclinicalpractice AT abhisheksoni exploringthemanagementofradiationproctitisincurrentclinicalpractice AT paramjeetkaur exploringthemanagementofradiationproctitisincurrentclinicalpractice AT ashokkumarchauhan exploringthemanagementofradiationproctitisincurrentclinicalpractice AT vivekkaushal exploringthemanagementofradiationproctitisincurrentclinicalpractice |
_version_ |
1724619218274484224 |