Conceptual Analogies Between Multi-Scale Feeding and Feedback Cycles in Supermassive Black Hole and Cancer Environments

Conceptual Analogies Between Multi-Scale Feeding and Feedback Cycles in Supermassive Black Hole and Cancer Environments

Adopting three physically-motivated scales (“micro” – “meso” – “macro”, which refer to mpc – kpc – Mpc, respectively) is paramount for achieving a unified theory of multiphase active galactic nuclei feeding and feedback, and it represents a keystone for astrophysical simulations and observations in...

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Main Authors: Matteo Santoni, Francesco Tombesi, Alessia Cimadamore, Rodolfo Montironi, Francesco Piva
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Oncology
Subjects:
cancer microenvironment
exosomes
metastasis
multi-scale feeding and feedback cycles
supermassive black holes
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.634818/full
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spelling doaj-7f3a38a1c46d4266bc81f33c1d4205152021-05-11T07:05:32ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2021-05-011110.3389/fonc.2021.634818634818Conceptual Analogies Between Multi-Scale Feeding and Feedback Cycles in Supermassive Black Hole and Cancer EnvironmentsMatteo Santoni0Francesco Tombesi1Francesco Tombesi2Francesco Tombesi3Francesco Tombesi4Alessia Cimadamore5Rodolfo Montironi6Francesco Piva7Oncology Unit, Macerata Hospital, Macerata, ItalyPhysics Department, University of Rome “Tor Vergata”, Rome, ItalyIstituto Nazionale di Astrofisica, Astronomical Observatory of Rome, Monte Porzio Catone, ItalyDepartment of Astronomy, University of Maryland Department of Astronomy, College Park, Maryland, MD, United StatesNational Aeronautics and Space Administration/Goddard Space Flight Center, Greenbelt, MD, United StatesSection of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, ItalySection of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, ItalyDepartment of Specialistic Clinical and Odontostomatological Sciences, Polytechnic University of Marche, Ancona, ItalyAdopting three physically-motivated scales (“micro” – “meso” – “macro”, which refer to mpc – kpc – Mpc, respectively) is paramount for achieving a unified theory of multiphase active galactic nuclei feeding and feedback, and it represents a keystone for astrophysical simulations and observations in the upcoming years. In order to promote this multi-scale idea, we have decided to adopt an interdisciplinary approach, exploring the possible conceptual similarities between supermassive black hole feeding and feedback cycles and the dynamics occurring in human cancer microenvironment.https://www.frontiersin.org/articles/10.3389/fonc.2021.634818/fullcancer microenvironmentexosomesmetastasismulti-scale feeding and feedback cyclessupermassive black holes
collection DOAJ
language English
format Article
sources DOAJ
author Matteo Santoni
Francesco Tombesi
Francesco Tombesi
Francesco Tombesi
Francesco Tombesi
Alessia Cimadamore
Rodolfo Montironi
Francesco Piva
spellingShingle Matteo Santoni
Francesco Tombesi
Francesco Tombesi
Francesco Tombesi
Francesco Tombesi
Alessia Cimadamore
Rodolfo Montironi
Francesco Piva
Conceptual Analogies Between Multi-Scale Feeding and Feedback Cycles in Supermassive Black Hole and Cancer Environments
Frontiers in Oncology
cancer microenvironment
exosomes
metastasis
multi-scale feeding and feedback cycles
supermassive black holes
author_facet Matteo Santoni
Francesco Tombesi
Francesco Tombesi
Francesco Tombesi
Francesco Tombesi
Alessia Cimadamore
Rodolfo Montironi
Francesco Piva
author_sort Matteo Santoni
title Conceptual Analogies Between Multi-Scale Feeding and Feedback Cycles in Supermassive Black Hole and Cancer Environments
title_short Conceptual Analogies Between Multi-Scale Feeding and Feedback Cycles in Supermassive Black Hole and Cancer Environments
title_full Conceptual Analogies Between Multi-Scale Feeding and Feedback Cycles in Supermassive Black Hole and Cancer Environments
title_fullStr Conceptual Analogies Between Multi-Scale Feeding and Feedback Cycles in Supermassive Black Hole and Cancer Environments
title_full_unstemmed Conceptual Analogies Between Multi-Scale Feeding and Feedback Cycles in Supermassive Black Hole and Cancer Environments
title_sort conceptual analogies between multi-scale feeding and feedback cycles in supermassive black hole and cancer environments
publisher Frontiers Media S.A.
series Frontiers in Oncology
issn 2234-943X
publishDate 2021-05-01
description Adopting three physically-motivated scales (“micro” – “meso” – “macro”, which refer to mpc – kpc – Mpc, respectively) is paramount for achieving a unified theory of multiphase active galactic nuclei feeding and feedback, and it represents a keystone for astrophysical simulations and observations in the upcoming years. In order to promote this multi-scale idea, we have decided to adopt an interdisciplinary approach, exploring the possible conceptual similarities between supermassive black hole feeding and feedback cycles and the dynamics occurring in human cancer microenvironment.
topic cancer microenvironment
exosomes
metastasis
multi-scale feeding and feedback cycles
supermassive black holes
url https://www.frontiersin.org/articles/10.3389/fonc.2021.634818/full
work_keys_str_mv AT matteosantoni conceptualanalogiesbetweenmultiscalefeedingandfeedbackcyclesinsupermassiveblackholeandcancerenvironments
AT francescotombesi conceptualanalogiesbetweenmultiscalefeedingandfeedbackcyclesinsupermassiveblackholeandcancerenvironments
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