4-Chloropropofol enhances chloride currents in human hyperekplexic and artificial mutated glycine receptors

<p>Abstract</p> <p>Background</p> <p>The mammalian neurological disorder hereditary hyperekplexia can be attributed to various mutations of strychnine sensitive glycine receptors. The clinical symptoms of “startle disease” predominantly occur in the newborn leading to c...

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Bibliographic Details
Main Authors: de la Roche Jeanne, Leuwer Martin, Krampfl Klaus, Haeseler Gertrud, Dengler Reinhard, Buchholz Vanessa, Ahrens Jörg
Format: Article
Language:English
Published: BMC 2012-09-01
Series:BMC Neurology
Subjects:
Online Access:http://www.biomedcentral.com/1471-2377/12/104