The Emerging Role of Myeloid-Derived Suppressor Cells in the Glioma Immune Suppressive Microenvironment

The Emerging Role of Myeloid-Derived Suppressor Cells in the Glioma Immune Suppressive Microenvironment

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous group of myeloid progenitor and precursor cells at different stages of differentiation, which play an important role in tumor immunosuppression. Glioma is the most common and deadliest primary malignant tumor of the brain, and ample eviden...

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Bibliographic Details
Main Authors: Yajing Mi, Na Guo, Jing Luan, Jianghong Cheng, Zhifang Hu, Pengtao Jiang, Weilin Jin, Xingchun Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Immunology
Subjects:
MDSC
glioma
immunosuppression
tumor microenvironment
therapeutic target
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00737/full

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