A Bioinformatics Perspective on the Links Between Tetraspanin-Enriched Microdomains and Cardiovascular Pathophysiology

A Bioinformatics Perspective on the Links Between Tetraspanin-Enriched Microdomains and Cardiovascular Pathophysiology

Background: Tetraspanins and integrins are integral membrane proteins. Tetraspanins interact with integrins to modulate the dynamics of adhesion, migration, proliferation, and signaling in the form of membrane domains called tetraspanin-enriched microdomains (TEMs). TEMs also contain other cell adhe...

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Bibliographic Details
Main Authors: Ge Sun, Junxiong Chen, Yingjun Ding, Jonathan D. Wren, Fuyi Xu, Lu Lu, Yan Wang, Dao-wen Wang, Xin A. Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
angiogenesis
atherosclerosis
blood pressure
integrin
platelet
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.630471/full

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