Pharmacogenetics of tenofovir and emtricitabine penetration into cerebrospinal fluid
Background: Blood-cerebrospinal fluid (CSF) barrier transporters affect the influx and efflux of drugs. The antiretrovirals tenofovir and emtricitabine may be substrates of blood-brain barrier (BBB) and blood-CSF barrier transporters, but data are limited regarding the pharmacogenetics and pharmacok...
Main Authors: | Eric H. Decloedt, Phumla Z. Sinxadi, Lubbe Wiesner, John A. Joska, David W. Haas, Gary Maartens |
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Format: | Article |
Language: | English |
Published: |
AOSIS
2021-04-01
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Series: | Southern African Journal of HIV Medicine |
Subjects: | |
Online Access: | https://sajhivmed.org.za/index.php/hivmed/article/view/1206 |
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