Pancytopenia in pregnant patients with COVID-19 infection and vitamin B12 deficiency: a case report study
Background: Folate and vitamin B 12 deficiency can lead to pancytopenia in pregnancy. Some cases of pancytopenia due to COVID-19 infection have also been reported. The two cases that we present are related to the coincidence of pregnancy and deficiency of folic acid and vitamin B12 with COVID-19 in...
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Journal of Ideas in Health
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doaj-7f988c88cc404a869e12b6d055a2e5362021-07-22T07:15:30ZengJournal of Ideas in HealthJournal of Ideas in Health2645-92482021-07-014Special210.47108/jidhealth.Vol4.IssSpecial2.138Pancytopenia in pregnant patients with COVID-19 infection and vitamin B12 deficiency: a case report studyNeha Agarwal0Neha Khatri1Preeti Singh2Department of Obstetrics and Gynaecology, Maulana Azad Medical College, New Delhi, IndiaDepartment of Obstetrics and Gynaecology, Maulana Azad Medical College, New Delhi, IndiaDepartment of Obstetrics and Gynaecology, Maulana Azad Medical College, New Delhi, India Background: Folate and vitamin B 12 deficiency can lead to pancytopenia in pregnancy. Some cases of pancytopenia due to COVID-19 infection have also been reported. The two cases that we present are related to the coincidence of pregnancy and deficiency of folic acid and vitamin B12 with COVID-19 infection. Case presentation: A 26-year- woman G3P1L1A1 and 21-year-woman G2P1L1 presented with pancytopenia and mild COVID-19 infection. The antenatal period was uneventful, and both cases also had folate and vitamin B12 deficiency. They received blood products, folic acid, and vitamin B12 supplementation. COVID- 19 infection was managed well with analgesic and vital monitoring. Postpartum hemorrhage occurred in the second case, which was well managed with uterotonics. All laboratory parameters came out to be normal after three months of supplementation of folic acid and vitamin B12. Conclusion: Pancytopenia in pregnancy due to folate and vitamin B12 deficiency and COVID- 19 infection can be easily managed with timely intensive targeted therapy, but we should be extra vigilant while handling such complicated cases, keeping in mind all possible differential diagnoses for pancytopenia. https://jidhealth.com/index.php/jidhealth/article/view/138Pancytopenia, COVID- 19, Folate, Vitamin B12, Pregnancy, Megaloblastic Anemia, India |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Neha Agarwal Neha Khatri Preeti Singh |
spellingShingle |
Neha Agarwal Neha Khatri Preeti Singh Pancytopenia in pregnant patients with COVID-19 infection and vitamin B12 deficiency: a case report study Journal of Ideas in Health Pancytopenia, COVID- 19, Folate, Vitamin B12, Pregnancy, Megaloblastic Anemia, India |
author_facet |
Neha Agarwal Neha Khatri Preeti Singh |
author_sort |
Neha Agarwal |
title |
Pancytopenia in pregnant patients with COVID-19 infection and vitamin B12 deficiency: a case report study |
title_short |
Pancytopenia in pregnant patients with COVID-19 infection and vitamin B12 deficiency: a case report study |
title_full |
Pancytopenia in pregnant patients with COVID-19 infection and vitamin B12 deficiency: a case report study |
title_fullStr |
Pancytopenia in pregnant patients with COVID-19 infection and vitamin B12 deficiency: a case report study |
title_full_unstemmed |
Pancytopenia in pregnant patients with COVID-19 infection and vitamin B12 deficiency: a case report study |
title_sort |
pancytopenia in pregnant patients with covid-19 infection and vitamin b12 deficiency: a case report study |
publisher |
Journal of Ideas in Health |
series |
Journal of Ideas in Health |
issn |
2645-9248 |
publishDate |
2021-07-01 |
description |
Background: Folate and vitamin B 12 deficiency can lead to pancytopenia in pregnancy. Some cases of pancytopenia due to COVID-19 infection have also been reported. The two cases that we present are related to the coincidence of pregnancy and deficiency of folic acid and vitamin B12 with COVID-19 infection.
Case presentation: A 26-year- woman G3P1L1A1 and 21-year-woman G2P1L1 presented with pancytopenia and mild COVID-19 infection. The antenatal period was uneventful, and both cases also had folate and vitamin B12 deficiency. They received blood products, folic acid, and vitamin B12 supplementation. COVID- 19 infection was managed well with analgesic and vital monitoring. Postpartum hemorrhage occurred in the second case, which was well managed with uterotonics. All laboratory parameters came out to be normal after three months of supplementation of folic acid and vitamin B12.
Conclusion: Pancytopenia in pregnancy due to folate and vitamin B12 deficiency and COVID- 19 infection can be easily managed with timely intensive targeted therapy, but we should be extra vigilant while handling such complicated cases, keeping in mind all possible differential diagnoses for pancytopenia.
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topic |
Pancytopenia, COVID- 19, Folate, Vitamin B12, Pregnancy, Megaloblastic Anemia, India |
url |
https://jidhealth.com/index.php/jidhealth/article/view/138 |
work_keys_str_mv |
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