How lifespan associated genes modulate aging changes: lessons from analysis of longitudinal data

How lifespan associated genes modulate aging changes: lessons from analysis of longitudinal data

Background and Objective. The influence of genes on human lifespan is mediated by biological processes that characterize body’s functioning. The age trajectories of these processes contain important information about mechanisms linking aging, health and lifespan. The objective of this paper is to i...

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Bibliographic Details
Main Authors: Anatoliy I Yashin, Konstantin G Arbeev, Deqing eWu, Liubov S. Arbeeva, Alexander eKulminski, Igor eAkushevich, Irina eCulminskaya, Eric eStallard, Svetlana eUkraintseva
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-01-01
Series:Frontiers in Genetics
Subjects:
age trajectories
physiological variables
longevity genes
genetic dose
integrative genetic mortality model
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00003/full

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