Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma

<p>Abstract</p> <p>Background</p> <p>Genomic instability plays an important role in human cancers. We previously characterized genomic instability in esophageal squamous cell carcinomas (ESCC) in terms of loss of heterozygosity (LOH) and copy number (CN) changes in tumo...

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Bibliographic Details
Main Authors: Ding Ti, Taylor Philip R, Goldstein Alisa M, Wang Chaoyu, Yang Howard H, Clifford Robert J, Hu Nan, Lee Maxwell P
Format: Article
Language:English
Published: BMC 2010-10-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/11/576