Astaxanthin analogs, adonixanthin and lycopene, activate Nrf2 to prevent light-induced photoreceptor degeneration

Astaxanthin analogs, adonixanthin and lycopene, activate Nrf2 to prevent light-induced photoreceptor degeneration

Carotenoids, in particular astaxanthin, possess potent antioxidant capabilities. Astaxanthin also induces NF-E2-related factor 2 (Nrf2), which plays a major regulatory role in the antioxidative response. However, little is known whether the carotenoid, by-products of astaxanthin, activate Nrf2. Towa...

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Bibliographic Details
Main Authors: Yuki Inoue, Masamitsu Shimazawa, Ryota Nagano, Yoshiki Kuse, Kei Takahashi, Kazuhiro Tsuruma, Masahiro Hayashi, Takashi Ishibashi, Takashi Maoka, Hideaki Hara
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Journal of Pharmacological Sciences
Subjects:
Astaxanthin
Adonixanthin
Lycopene
Nrf2 activation
Photoreceptor
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861317300890

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http://www.sciencedirect.com/science/article/pii/S1347861317300890

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