Lycopene and intralesional betamethasone injections in the management of oral submucous fibrosis
Aims and Objectives: This study was conducted to determine the efficacy of lycopene in the management of oral submucous fibrosis (OSMF) and to compare its efficacy with intralesional betamethasone injections. Materials and Methods: Forty-four patients were divided randomly into two groups. Group I s...
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Wolters Kluwer Medknow Publications
2014-01-01
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doaj-7fc16bbbc8ff412fb2fb4792dfa35a072020-11-24T23:29:31ZengWolters Kluwer Medknow PublicationsJournal of Indian Academy of Oral Medicine and Radiology0972-13630975-15722014-01-0126326426810.4103/0972-1363.145000Lycopene and intralesional betamethasone injections in the management of oral submucous fibrosisDipti SinghMathod C ShashikanthNeeta MisraSudhanshu AgrawalAims and Objectives: This study was conducted to determine the efficacy of lycopene in the management of oral submucous fibrosis (OSMF) and to compare its efficacy with intralesional betamethasone injections. Materials and Methods: Forty-four patients were divided randomly into two groups. Group I subjects were treated with 10,000 mcg of lycopene (Lyconex) daily, in two equally divided doses, for two months. Group II subjects were given intralesional injections of betamethasone. Both the groups were assessed in terms of mouth opening and burning sensation. Results: A significant improvement in mouth opening was seen in both the groups and the improvement was better in Group I. The mean improvement in mouth opening in Group I was 37.62% (12 mm) at the end of the study, which was statistically highly significant and weekly evaluation revealed that this high significance was from the third week onward, and Group II patients (only intralesional steroids) showed an average improvement of 13% (3.9 mm) at the final follow-up visit. Conclusion: Lycopene (Lyconex) is better than intralesional betamethasone injections in improving mouth opening and decreasing burning sensation.http://www.jiaomr.in/article.asp?issn=0972-1363;year=2014;volume=26;issue=3;spage=264;epage=268;aulast=SinghEfficacyintralesionallycopenemanagementoral submucous fibrosissteroids |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Dipti Singh Mathod C Shashikanth Neeta Misra Sudhanshu Agrawal |
spellingShingle |
Dipti Singh Mathod C Shashikanth Neeta Misra Sudhanshu Agrawal Lycopene and intralesional betamethasone injections in the management of oral submucous fibrosis Journal of Indian Academy of Oral Medicine and Radiology Efficacy intralesional lycopene management oral submucous fibrosis steroids |
author_facet |
Dipti Singh Mathod C Shashikanth Neeta Misra Sudhanshu Agrawal |
author_sort |
Dipti Singh |
title |
Lycopene and intralesional betamethasone injections in the management of oral submucous fibrosis |
title_short |
Lycopene and intralesional betamethasone injections in the management of oral submucous fibrosis |
title_full |
Lycopene and intralesional betamethasone injections in the management of oral submucous fibrosis |
title_fullStr |
Lycopene and intralesional betamethasone injections in the management of oral submucous fibrosis |
title_full_unstemmed |
Lycopene and intralesional betamethasone injections in the management of oral submucous fibrosis |
title_sort |
lycopene and intralesional betamethasone injections in the management of oral submucous fibrosis |
publisher |
Wolters Kluwer Medknow Publications |
series |
Journal of Indian Academy of Oral Medicine and Radiology |
issn |
0972-1363 0975-1572 |
publishDate |
2014-01-01 |
description |
Aims and Objectives: This study was conducted to determine the efficacy of lycopene in the management of oral submucous fibrosis (OSMF) and to compare its efficacy with intralesional betamethasone injections. Materials and Methods: Forty-four patients were divided randomly into two groups. Group I subjects were treated with 10,000 mcg of lycopene (Lyconex) daily, in two equally divided doses, for two months. Group II subjects were given intralesional injections of betamethasone. Both the groups were assessed in terms of mouth opening and burning sensation. Results: A significant improvement in mouth opening was seen in both the groups and the improvement was better in Group I. The mean improvement in mouth opening in Group I was 37.62% (12 mm) at the end of the study, which was statistically highly significant and weekly evaluation revealed that this high significance was from the third week onward, and Group II patients (only intralesional steroids) showed an average improvement of 13% (3.9 mm) at the final follow-up visit. Conclusion: Lycopene (Lyconex) is better than intralesional betamethasone injections in improving mouth opening and decreasing burning sensation. |
topic |
Efficacy intralesional lycopene management oral submucous fibrosis steroids |
url |
http://www.jiaomr.in/article.asp?issn=0972-1363;year=2014;volume=26;issue=3;spage=264;epage=268;aulast=Singh |
work_keys_str_mv |
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