Quantification of liver fibrosis: extracellular volume fraction using an MRI bolus-only technique in a rat animal model
Abstract Background To determine the utility of single-contrast-bolus hepatic extracellular volume (ECV) fraction measurement at different time points to detect and quantify hepatic fibrosis. Methods Different grades of liver fibrosis were induced in 23 male Sprague-Dawley rats by carbon-tetrachlori...
Main Authors: | Julian A. Luetkens, Sabine Klein, Frank Träber, Wolfgang Block, Frederic C. Schmeel, Alois M. Sprinkart, Daniel L. R. Kuetting, Frank E. Uschner, Robert Schierwagen, Daniel Thomas, Jonel Trebicka, Guido M. Kukuk |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2019-05-01
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Series: | European Radiology Experimental |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s41747-019-0100-y |
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