Gene-environment interactions mediate stress susceptibility and resilience through the CaMKIIβ/TARPγ-8/AMPAR pathway
Summary: Although stressful events predispose individuals to psychiatric disorders, such as depression, not all people who undergo a stressful life experience become depressed, suggesting that gene-environment interactions (GxE) determine depression risk. The ventral hippocampus (vHPC) plays key rol...
Main Authors: | Yusuke Sakai, Haiyan Li, Hiromichi Inaba, Yuki Funayama, Erina Ishimori, Ayako Kawatake-Kuno, Hirotaka Yamagata, Tomoe Seki, Teruyuki Hobara, Shin Nakagawa, Yoshifumi Watanabe, Susumu Tomita, Toshiya Murai, Shusaku Uchida |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2021-05-01
|
Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004221004727 |
Similar Items
-
Memories Are Made of This: Modeling the CaMKII Molecular Switch
Published: (2005-01-01) -
Characterization of six CaMKIIα variants found in patients with schizophrenia
by: Carolyn Nicole Brown, et al.
Published: (2021-10-01) -
The Stability of a Stochastic CaMKII Switch: Dependence on the Number of Enzyme Molecules and Protein Turnover
by: Miller Paul, et al.
Published: (2005-01-01) -
The role of L-lactate in NMDAR-CaMKIIα Interaction
by: Alamoudi, Rayyan T.
Published: (2019) -
Reward boosts reinforcement-based motor learning
by: Pierre Vassiliadis, et al.
Published: (2021-07-01)