Biphasic Production of Anti-ApoB100 Autoantibodies in Obese Humans and Mice
Obesity is associated with autoimmunity, a phenomenon considered as harmful. Here we show that obese mice and humans produce IgG-type autoantibodies that specifically recognize apolipoprotein B-100 (ApoB100), its native epitope p210, and the synthetic p210 mimotope pB1. By contrast, antibodies again...
Main Authors: | Moon Kyung Choe, Hyung-Ji Kim, Nan Hee Kim, Bert Binas, Hyo Joon Kim |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-04-01
|
Series: | Pharmaceuticals |
Subjects: | |
Online Access: | https://www.mdpi.com/1424-8247/14/4/330 |
Similar Items
-
A monoclonal antibody to assess oxidized cholesteryl esters associated with apoAI and apoB-100 lipoproteins in human plasma1[S]
by: Ayelet Gonen, et al.
Published: (2019-02-01) -
Peptide mimotopes of malondialdehyde epitopes for clinical applications in cardiovascular disease
by: Shahzada Amir, et al.
Published: (2012-07-01) -
Identification of autoantibodies in human plasma recognizing an apoB-100 LDL receptor binding site peptide
by: Gunilla Nordin Fredrikson, et al.
Published: (2006-09-01) -
Role of Natural Autoantibodies (NAA) and Natural IgM Anti-leucocyte autoantibodies (IgM-ALA) in Health and Disease
by: Peter Isaac Lobo
Published: (2016-06-01) -
Potential SARS-CoV-2 Preimmune IgM Epitopes
by: Velizar Shivarov, et al.
Published: (2020-04-01)