Solid-lipid nanoparticle formulation improves antiseizure action of cryptolepine
Following the high treatment gap and massive impact of epilepsy on global health particularly in low- and middle-income countries, our study aims to investigate cryptolepine, the major alkaloid of Cryptolepis sanguinolenta as well as its solid-lipid nanoparticle formulation for potential antiseizure...
Main Authors: | Priscilla Kolibea Mante, Nana Ofori Adomako, Paulina Antwi, Nana Kofi Kusi-Boadum, Newman Osafo |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2021-05-01
|
Series: | Biomedicine & Pharmacotherapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332221001396 |
Similar Items
-
Chronic administration of cryptolepine nanoparticle formulation alleviates seizures in a neurocysticercosis model
by: Priscilla Kolibea Mante, et al.
Published: (2021-01-01) -
Anti-inflammatory properties of cryptolepine.
by: Olajide, O.A., et al.
Published: (2010) -
Identification of cryptolepine metabolites in rat and human hepatocytes and metabolism and pharmacokinetics of cryptolepine in Sprague Dawley rats
by: Arnold Donkor Forkuo, et al.
Published: (2017-12-01) -
In vitro anti-malarial interaction and gametocytocidal activity of cryptolepine
by: Arnold Donkor Forkuo, et al.
Published: (2017-12-01) -
LEAP2 Impairs the Capability of the Growth Hormone Secretagogue Receptor to Regulate the Dopamine 2 Receptor Signaling
by: Emilio R. Mustafá, et al.
Published: (2021-08-01)