Ranking genomic features using an information-theoretic measure of epigenetic discordance
Abstract Background Establishment and maintenance of DNA methylation throughout the genome is an important epigenetic mechanism that regulates gene expression whose disruption has been implicated in human diseases like cancer. It is therefore crucial to know which genes, or other genomic features of...
Main Authors: | Garrett Jenkinson, Jordi Abante, Michael A. Koldobskiy, Andrew P. Feinberg, John Goutsias |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-04-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-019-2777-6 |
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