Genotyping and Copy Number Analysis of Immunoglobin Heavy Chain Variable Genes Using Long Reads
Summary: One of the remaining challenges to describing an individual's genetic variation lies in the highly heterogeneous and complex genomic regions that impede the use of classical reference-guided mapping and assembly approaches. Once such region is the Immunoglobulin heavy chain locus (IGH)...
Main Authors: | Michael Ford, Ehsan Haghshenas, Corey T. Watson, S. Cenk Sahinalp |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-03-01
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Series: | iScience |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004220300675 |
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