Urate Oxidase Knockdown Decreases Oxidative Stress in a Murine Hepatic Cell Line
Humans, birds, and some primates do not express the uric acid degrading enzyme urate oxidase (UOX) and, as a result, have plasma uric acid concentrations higher than UOX expressing animals. Although high uric acid concentrations are suggested to increase the antioxidant defense system and provide a...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2009-01-01
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| Series: | Oxidative Medicine and Cellular Longevity |
| Online Access: | http://dx.doi.org/10.4161/oxim.2.2.8372 |