Antigen-Specific Treatment Modalities in MS: The Past, the Present, and the Future
Antigen-specific therapy for multiple sclerosis may lead to a more effective therapy by induction of tolerance to a wide range of myelin-derived antigens without hampering the normal surveillance and effector function of the immune system. Numerous attempts to restore tolerance toward myelin-derived...
Main Authors: | Judith Derdelinckx, Patrick Cras, Zwi N. Berneman, Nathalie Cools |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-02-01
|
Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2021.624685/full |
Similar Items
-
Clinical and immunological control of experimental autoimmune encephalomyelitis by tolerogenic dendritic cells loaded with MOG-encoding mRNA
by: Judith Derdelinckx, et al.
Published: (2019-08-01) -
HLA Class II Genotype Does Not Affect the Myelin Responsiveness of Multiple Sclerosis Patients
by: Judith Derdelinckx, et al.
Published: (2020-12-01) -
Targeted Expression of Myelin Autoantigen in the Periphery Induces Antigen-Specific T and B Cell Tolerance and Ameliorates Autoimmune Disease
by: Shin-Young Na, et al.
Published: (2021-06-01) -
Sevoflurane reduces clinical disease in a mouse model of multiple sclerosis
by: Polak Paul E, et al.
Published: (2012-12-01) -
Shuttling Tolerogenic Dendritic Cells across the Blood–Brain Barrier In Vitro via the Introduction of De Novo C–C Chemokine Receptor 5 Expression Using Messenger RNA Electroporation
by: Maxime De Laere, et al.
Published: (2018-01-01)