Correlation between turbidimetric and nephelometric methods of measuring C-reactive protein in patients with unstable angina or non-ST elevation acute myocardial infarction
OBJECTIVE: To evaluate the performance of the turbidimetric method of C-reactive protein (CRP) as a measure of low-grade inflammation in patients admitted with non-ST elevation acute coronary syndromes (ACS). METHODS: Serum samples obtained at hospital arrival from 68 patients (66±11 years, 40 men),...
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Sociedade Brasileira de Cardiologia (SBC)
2003-08-01
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doaj-80229c56fe1a4fbd878a995cd559f0df2020-11-24T23:43:09ZengSociedade Brasileira de Cardiologia (SBC)Arquivos Brasileiros de Cardiologia0066-782X1678-41702003-08-0181213313610.1590/S0066-782X2003001000002Correlation between turbidimetric and nephelometric methods of measuring C-reactive protein in patients with unstable angina or non-ST elevation acute myocardial infarctionLuis C. L. CorreiaJosé C. LimaGary GerstenblithLuis P. MagalhãesAgnaluce MoreiraOctávio Barbosa Jr.Juliana DumetLuiz Carlos S. PassosArgemiro D'Oliveira JúniorJosé Péricles EstevesOBJECTIVE: To evaluate the performance of the turbidimetric method of C-reactive protein (CRP) as a measure of low-grade inflammation in patients admitted with non-ST elevation acute coronary syndromes (ACS). METHODS: Serum samples obtained at hospital arrival from 68 patients (66±11 years, 40 men), admitted with unstable angina or non-ST elevation acute myocardial infarction were used to measure CRP by the methods of nephelometry and turbidimetry. RESULTS: The medians of C-reactive protein by the turbidimetric and nephelometric methods were 0.5 mg/dL and 0.47 mg/dL, respectively. A strong linear association existed between the 2 methods, according to the regression coefficient (b=0.75; 95% C.I.=0.70-0.80) and correlation coefficient (r=0.96; P<0.001). The mean difference between the nephelometric and turbidimetric CRP was 0.02 ± 0.91 mg/dL, and 100% agreement between the methods in the detection of high CRP was observed. CONCLUSION: In patients with non-ST elevation ACS, CRP values obtained by turbidimetry show a strong linear association with the method of nephelometry and perfect agreement in the detection of high CRP.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2003001000002C-reactive proteinturbidimetric methodacute coronary syndromes |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Luis C. L. Correia José C. Lima Gary Gerstenblith Luis P. Magalhães Agnaluce Moreira Octávio Barbosa Jr. Juliana Dumet Luiz Carlos S. Passos Argemiro D'Oliveira Júnior José Péricles Esteves |
spellingShingle |
Luis C. L. Correia José C. Lima Gary Gerstenblith Luis P. Magalhães Agnaluce Moreira Octávio Barbosa Jr. Juliana Dumet Luiz Carlos S. Passos Argemiro D'Oliveira Júnior José Péricles Esteves Correlation between turbidimetric and nephelometric methods of measuring C-reactive protein in patients with unstable angina or non-ST elevation acute myocardial infarction Arquivos Brasileiros de Cardiologia C-reactive protein turbidimetric method acute coronary syndromes |
author_facet |
Luis C. L. Correia José C. Lima Gary Gerstenblith Luis P. Magalhães Agnaluce Moreira Octávio Barbosa Jr. Juliana Dumet Luiz Carlos S. Passos Argemiro D'Oliveira Júnior José Péricles Esteves |
author_sort |
Luis C. L. Correia |
title |
Correlation between turbidimetric and nephelometric methods of measuring C-reactive protein in patients with unstable angina or non-ST elevation acute myocardial infarction |
title_short |
Correlation between turbidimetric and nephelometric methods of measuring C-reactive protein in patients with unstable angina or non-ST elevation acute myocardial infarction |
title_full |
Correlation between turbidimetric and nephelometric methods of measuring C-reactive protein in patients with unstable angina or non-ST elevation acute myocardial infarction |
title_fullStr |
Correlation between turbidimetric and nephelometric methods of measuring C-reactive protein in patients with unstable angina or non-ST elevation acute myocardial infarction |
title_full_unstemmed |
Correlation between turbidimetric and nephelometric methods of measuring C-reactive protein in patients with unstable angina or non-ST elevation acute myocardial infarction |
title_sort |
correlation between turbidimetric and nephelometric methods of measuring c-reactive protein in patients with unstable angina or non-st elevation acute myocardial infarction |
publisher |
Sociedade Brasileira de Cardiologia (SBC) |
series |
Arquivos Brasileiros de Cardiologia |
issn |
0066-782X 1678-4170 |
publishDate |
2003-08-01 |
description |
OBJECTIVE: To evaluate the performance of the turbidimetric method of C-reactive protein (CRP) as a measure of low-grade inflammation in patients admitted with non-ST elevation acute coronary syndromes (ACS). METHODS: Serum samples obtained at hospital arrival from 68 patients (66±11 years, 40 men), admitted with unstable angina or non-ST elevation acute myocardial infarction were used to measure CRP by the methods of nephelometry and turbidimetry. RESULTS: The medians of C-reactive protein by the turbidimetric and nephelometric methods were 0.5 mg/dL and 0.47 mg/dL, respectively. A strong linear association existed between the 2 methods, according to the regression coefficient (b=0.75; 95% C.I.=0.70-0.80) and correlation coefficient (r=0.96; P<0.001). The mean difference between the nephelometric and turbidimetric CRP was 0.02 ± 0.91 mg/dL, and 100% agreement between the methods in the detection of high CRP was observed. CONCLUSION: In patients with non-ST elevation ACS, CRP values obtained by turbidimetry show a strong linear association with the method of nephelometry and perfect agreement in the detection of high CRP. |
topic |
C-reactive protein turbidimetric method acute coronary syndromes |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2003001000002 |
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