Inferring the Disease-Associated miRNAs Based on Network Representation Learning and Convolutional Neural Networks

Inferring the Disease-Associated miRNAs Based on Network Representation Learning and Convolutional Neural Networks

Identification of disease-associated miRNAs (disease miRNAs) are critical for understanding etiology and pathogenesis. Most previous methods focus on integrating similarities and associating information contained in heterogeneous miRNA-disease networks. However, these methods establish only shallow...

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Bibliographic Details
Main Authors: Ping Xuan, Hao Sun, Xiao Wang, Tiangang Zhang, Shuxiang Pan
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:International Journal of Molecular Sciences
Subjects:
disease-associated miRNAs
network representation learning
convolutional neural network
non-negative matrix factorization
deep learning
Online Access:https://www.mdpi.com/1422-0067/20/15/3648

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