A single-step synthesis of nitrogen-doped graphene sheets decorated with cobalt hydroxide nanoflakes for the determination of dopamine

• Main Authors: Muhammad Mehmood Shahid, Ahmad H. Ismail, Ali MA. Abdul Amir AL-Mokaram, R. Vikneswaran, Sohail Ahmad, Amir Hamza, Arshid Numan
• Format: Article
• Language: English
• Published: Elsevier 2017-10-01
• Series: Progress in Natural Science: Materials International
• Online Access: http://www.sciencedirect.com/science/article/pii/S1002007117305397
• ISSN: 1002-0071

Nitrogen-doped reduced graphene oxide (NrGO) sheets decorated with Co(OH)2 nanoflakes were prepared by a single-step hydrothermal process. The morphological and structural characterizations of as synthesized NrGO@Co(OH)2 nanoflakes were performed by field emission scanning electron microscopy (FESEM), EDX-mapping and X-ray diffraction (XRD). NrGO@Co(OH)2 nanoflakes modified glassy carbon electrode (GCE) was used for electrochemical sensing of dopamine in neutral medium. The nanocomposite modified electrode showed enhanced electrochemical sensing ability for the detection of dopamine and the limit of detection (LoD) was found to be 0.201 μM with a sensitivity value of 0.0286 ± 0.002 mA mMâ1. Interference studies revealed that NrGO@Co(OH)2âGCE endow excellent selectivity for DA detection even in the presence of higher concentration of common co-existing physiological interfering analytes. Additionally, proposed sensor demonstrated excellent performance in urine samples with promising reproducibility and stability. Keywords: Nitrogen doped graphene, Dopamine, Electrochemical sensor, Amperometric detection