Neonatal Mesenchymal Stem Cell Treatment Improves Myelination Impaired by Global Perinatal Asphyxia in Rats

Neonatal Mesenchymal Stem Cell Treatment Improves Myelination Impaired by Global Perinatal Asphyxia in Rats

The effect of perinatal asphyxia (PA) on oligodendrocyte (OL), neuroinflammation, and cell viability was evaluated in telencephalon of rats at postnatal day (P)1, 7, and 14, a period characterized by a spur of neuronal networking, evaluating the effect of mesenchymal stem cell (MSCs)-treatment. The...

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Bibliographic Details
Main Authors: Andrea Tapia-Bustos, Carolyne Lespay-Rebolledo, Valentina Vío, Ronald Pérez-Lobos, Emmanuel Casanova-Ortiz, Fernando Ezquer, Mario Herrera-Marschitz, Paola Morales
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
hypomyelination
oligodendrocyte
myelination
neonatal asphyxia/ischemia
apoptosis
mesenchymal stem cells
Online Access:https://www.mdpi.com/1422-0067/22/6/3275

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