In Vitro Analysis of Pyrogenicity and Cytotoxicity Profiles of Flex Sensors to be Used to Sense Human Joint Postures
Flex sensors can be usefully adopted as mechanical-electrical transducers to measure human joint movements, since their electrical resistance varies proportionally to the angle assumed by the joint under measure. Over time, these sensors have been investigated in terms of mechanical and electrical b...
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doaj-8093f3bd31c041bb92b9a3181b4514b02020-11-25T00:51:36ZengMDPI AGSensors1424-82202014-07-01147116721168110.3390/s140711672s140711672In Vitro Analysis of Pyrogenicity and Cytotoxicity Profiles of Flex Sensors to be Used to Sense Human Joint PosturesGiovanni Saggio0Luigi Bianchi1Silvia Castelli2Marilina B. Santucci3Maurizio Fraziano4Alessandro Desideri5Department of Electronic Engineering, University of Tor Vergata, via del Politecnico, 1-00133 Rome, ItalyDepartment of Civil Engineering and Computer Science, University of Tor Vergata, via del Politecnico, 1-00133 Rome, ItalyDepartment of Biology, University of Tor Vergata, Via della Ricerca Scientifica, 1-00173 Rome, ItalyDepartment of Biology, University of Tor Vergata, Via della Ricerca Scientifica, 1-00173 Rome, ItalyDepartment of Biology, University of Tor Vergata, Via della Ricerca Scientifica, 1-00173 Rome, ItalyDepartment of Biology, University of Tor Vergata, Via della Ricerca Scientifica, 1-00173 Rome, ItalyFlex sensors can be usefully adopted as mechanical-electrical transducers to measure human joint movements, since their electrical resistance varies proportionally to the angle assumed by the joint under measure. Over time, these sensors have been investigated in terms of mechanical and electrical behavior, but no reports have detailed the possibility of their adoption not just on top but under the human skin of the joint. To this aim, our work investigated in vitro the pyrogenic potential and cytotoxicity of some commercially available flex sensors as a first step toward the necessary requirements regarding their biocompatibility, to predict possible foreign body reactions when used in vivo. Results demonstrated that some specific flex sensors satisfy such requirements.http://www.mdpi.com/1424-8220/14/7/11672flex sensorspyrogenic potentialcytotoxicitybiocompatibilityhuman joints |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Giovanni Saggio Luigi Bianchi Silvia Castelli Marilina B. Santucci Maurizio Fraziano Alessandro Desideri |
spellingShingle |
Giovanni Saggio Luigi Bianchi Silvia Castelli Marilina B. Santucci Maurizio Fraziano Alessandro Desideri In Vitro Analysis of Pyrogenicity and Cytotoxicity Profiles of Flex Sensors to be Used to Sense Human Joint Postures Sensors flex sensors pyrogenic potential cytotoxicity biocompatibility human joints |
author_facet |
Giovanni Saggio Luigi Bianchi Silvia Castelli Marilina B. Santucci Maurizio Fraziano Alessandro Desideri |
author_sort |
Giovanni Saggio |
title |
In Vitro Analysis of Pyrogenicity and Cytotoxicity Profiles of Flex Sensors to be Used to Sense Human Joint Postures |
title_short |
In Vitro Analysis of Pyrogenicity and Cytotoxicity Profiles of Flex Sensors to be Used to Sense Human Joint Postures |
title_full |
In Vitro Analysis of Pyrogenicity and Cytotoxicity Profiles of Flex Sensors to be Used to Sense Human Joint Postures |
title_fullStr |
In Vitro Analysis of Pyrogenicity and Cytotoxicity Profiles of Flex Sensors to be Used to Sense Human Joint Postures |
title_full_unstemmed |
In Vitro Analysis of Pyrogenicity and Cytotoxicity Profiles of Flex Sensors to be Used to Sense Human Joint Postures |
title_sort |
in vitro analysis of pyrogenicity and cytotoxicity profiles of flex sensors to be used to sense human joint postures |
publisher |
MDPI AG |
series |
Sensors |
issn |
1424-8220 |
publishDate |
2014-07-01 |
description |
Flex sensors can be usefully adopted as mechanical-electrical transducers to measure human joint movements, since their electrical resistance varies proportionally to the angle assumed by the joint under measure. Over time, these sensors have been investigated in terms of mechanical and electrical behavior, but no reports have detailed the possibility of their adoption not just on top but under the human skin of the joint. To this aim, our work investigated in vitro the pyrogenic potential and cytotoxicity of some commercially available flex sensors as a first step toward the necessary requirements regarding their biocompatibility, to predict possible foreign body reactions when used in vivo. Results demonstrated that some specific flex sensors satisfy such requirements. |
topic |
flex sensors pyrogenic potential cytotoxicity biocompatibility human joints |
url |
http://www.mdpi.com/1424-8220/14/7/11672 |
work_keys_str_mv |
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