The p38 MAPK and NF-κB Pathways are Involved in Cyclic Compressive Force-induced IL-6 Secretion in MLO-Y4 Cells

The p38 MAPK and NF-κB Pathways are Involved in Cyclic Compressive Force-induced IL-6 Secretion in MLO-Y4 Cells

ABSTRACT We previously revealed the involvement of extracellular regulated protein kinases 1/2 (ERK1/2) in interleukin-6 (IL-6) secretion induced by cyclic compressive force (CCF) in MLO-Y4 cells. In this study, we investigated the contributions of the p38 mitogen-activated protein kinase (MAPK) and...

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Bibliographic Details
Main Authors: Xiwen Chen, Wenchuan Chen, Yun He, Yixin Zhang, Chenfeng Chen, Zhimin Zhu, Hang Wang
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2018-11-01
Series:Brazilian Archives of Biology and Technology
Subjects:
interleukin-6
cyclic compressive force
p38 mitogen-activated protein kinases
nuclear factor-κB
osteocyte
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100437&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100437&lng=en&tlng=en

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