BIIB021: A novel inhibitor to heat shock protein 90–addicted oncology

BIIB021: A novel inhibitor to heat shock protein 90–addicted oncology

Heat shock protein 90 is induced in response to the cell stress. Its overexpression has been reported in many cancers with poor prognosis. It acts as a chaperone to the client proteins, especially the activated oncoproteins in malignancies to protect them from degradation. Heat shock protein 90 inhi...

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Bibliographic Details
Main Authors:	Liang Yan, Weiming Zhang, Beibei Zhang, Chao Xuan, Daogang Wang
Format:	Article
Language:	English
Published:	IOS Press 2017-04-01
Series:	Tumor Biology
Online Access:	https://doi.org/10.1177/1010428317698355

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