Atypical PKCs activate Vimentin to facilitate prostate cancer cell motility and invasion

Atypical PKCs activate Vimentin to facilitate prostate cancer cell motility and invasion

Atypical protein kinase C (aPKC) are involved in progression of many human cancers. Vimentin is expressed during epithelial to mesenchymal transition (EMT). Molecular dynamics of Vimentin intermediate filaments (VIFs) play a key role in metastasis. This article is an effort to provide thorough under...

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Bibliographic Details
Main Authors: Wishrawana S. Ratnayake, Christopher A. Apostolatos, Sloan Breedy, Clare L. Dennison, Robert Hill, Mildred Acevedo-Duncan
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Cell Adhesion & Migration
Subjects:
pkc-ι
pkc-ζ
vimentin dynamics
phosphorylation
metastasis
prostate cancer
Online Access:http://dx.doi.org/10.1080/19336918.2021.1882782

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