Fundamental Roles of the Golgi-Associated Toxoplasma Aspartyl Protease, ASP5, at the Host-Parasite Interface.

Toxoplasma gondii possesses sets of dense granule proteins (GRAs) that either assemble at, or cross the parasitophorous vacuole membrane (PVM) and exhibit motifs resembling the HT/PEXEL previously identified in a repertoire of exported Plasmodium proteins. Within Plasmodium spp., cleavage of the HT/...

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Main Authors: Pierre-Mehdi Hammoudi, Damien Jacot, Christina Mueller, Manlio Di Cristina, Sunil Kumar Dogga, Jean-Baptiste Marq, Julia Romano, Nicolò Tosetti, Juan Dubrot, Yalin Emre, Matteo Lunghi, Isabelle Coppens, Masahiro Yamamoto, Daniel Sojka, Paco Pino, Dominique Soldati-Favre
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4608785?pdf=render