NEDDylation promotes stress granule assembly

Stress granules that form in response to stress contain translationally stalled mRNPs and play important roles in cellular homeostasis. Here the authors implicate SRSF3 neddylation as an important factor in the formation of stress granules in response to arsenite exposure.

Bibliographic Details
Main Authors:	Aravinth Kumar Jayabalan, Anthony Sanchez, Ra Young Park, Sang Pil Yoon, Gum-Yong Kang, Je-Hyun Baek, Paul Anderson, Younghoon Kee, Takbum Ohn
Format:	Article
Language:	English
Published:	Nature Publishing Group 2016-07-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/ncomms12125

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spelling	doaj-81168d0d790b4089a2d9c56c3252fc662021-05-11T11:11:21ZengNature Publishing GroupNature Communications2041-17232016-07-017111410.1038/ncomms12125NEDDylation promotes stress granule assemblyAravinth Kumar Jayabalan0Anthony Sanchez1Ra Young Park2Sang Pil Yoon3Gum-Yong Kang4Je-Hyun Baek5Paul Anderson6Younghoon Kee7Takbum Ohn8Department of Cellular & Molecular Medicine, College of Medicine, Chosun UniversityDepartment of Cell Biology, Microbiology, and Molecular Biology, College of Arts and Sciences, University of South FloridaDepartment of Cellular & Molecular Medicine, College of Medicine, Chosun UniversityDepartment of Anatomy, School of Medicine, Jeju National UniversityDiatech Korea Co, LtdDiatech Korea Co, LtdDivision of Rheumatology, Immunology and Allergy, Brigham and Women’s HospitalDepartment of Cell Biology, Microbiology, and Molecular Biology, College of Arts and Sciences, University of South FloridaDepartment of Cellular & Molecular Medicine, College of Medicine, Chosun UniversityStress granules that form in response to stress contain translationally stalled mRNPs and play important roles in cellular homeostasis. Here the authors implicate SRSF3 neddylation as an important factor in the formation of stress granules in response to arsenite exposure.https://doi.org/10.1038/ncomms12125
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Aravinth Kumar Jayabalan Anthony Sanchez Ra Young Park Sang Pil Yoon Gum-Yong Kang Je-Hyun Baek Paul Anderson Younghoon Kee Takbum Ohn
spellingShingle	Aravinth Kumar Jayabalan Anthony Sanchez Ra Young Park Sang Pil Yoon Gum-Yong Kang Je-Hyun Baek Paul Anderson Younghoon Kee Takbum Ohn NEDDylation promotes stress granule assembly Nature Communications
author_facet	Aravinth Kumar Jayabalan Anthony Sanchez Ra Young Park Sang Pil Yoon Gum-Yong Kang Je-Hyun Baek Paul Anderson Younghoon Kee Takbum Ohn
author_sort	Aravinth Kumar Jayabalan
title	NEDDylation promotes stress granule assembly
title_short	NEDDylation promotes stress granule assembly
title_full	NEDDylation promotes stress granule assembly
title_fullStr	NEDDylation promotes stress granule assembly
title_full_unstemmed	NEDDylation promotes stress granule assembly
title_sort	neddylation promotes stress granule assembly
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2016-07-01
description	Stress granules that form in response to stress contain translationally stalled mRNPs and play important roles in cellular homeostasis. Here the authors implicate SRSF3 neddylation as an important factor in the formation of stress granules in response to arsenite exposure.
url	https://doi.org/10.1038/ncomms12125
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NEDDylation promotes stress granule assembly

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