Leptospira Interrogans induces fibrosis in the mouse kidney through Inos-dependent, TLR- and NLR-independent signaling pathways.

Leptospira Interrogans induces fibrosis in the mouse kidney through Inos-dependent, TLR- and NLR-independent signaling pathways.

BACKGROUND: Leptospira (L.) interrogans are bacteria responsible for a worldwide reemerging zoonosis. Rodents carry L. interrogans asymptomatically in their kidneys and excrete bacteria in the urine, contaminating the environment. Humans get infected through skin contact and develop a mild or severe...

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Main Authors: Martine Fanton d'Andon, Nathalie Quellard, Béatrice Fernandez, Gwenn Ratet, Sonia Lacroix-Lamandé, Alain Vandewalle, Ivo G Boneca, Jean-Michel Goujon, Catherine Werts
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3907306?pdf=render

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http://europepmc.org/articles/PMC3907306?pdf=render

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