Exaggerated serum levels of alpha-fetoprotein in focal nodular hyperplasia of the liver

Alpha-fetoprotein (AFP) is a tumor marker routinely used for the diagnosis and follow-up of malignant neoplasms. We report a case of extremely high serum levels of AFP associated with benign lesions of the liver and of the lungs with a spontaneous and gradual drop to normal values in the 9-month fol...

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Main Authors: Lorenzo Cirri, Farouk Dahmash, Christian Marin, Wolfram Grüning, Ahmet H. Elmaagacli
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Gastroenterology Insights
Subjects:
Online Access:http://www.pagepress.org/journals/index.php/gi/article/view/6399
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spelling doaj-81580a8790a74b20bb35f070c1e182712021-05-02T17:26:32ZengMDPI AGGastroenterology Insights2036-74142036-74222016-08-017110.4081/gi.2016.63993494Exaggerated serum levels of alpha-fetoprotein in focal nodular hyperplasia of the liverLorenzo Cirri0Farouk Dahmash1Christian Marin2Wolfram Grüning3Ahmet H. Elmaagacli4Departments of Hematology and Oncology, and Respiratory Medicine, Schwerin Medical CenterDepartment of Hematology and Oncology, Schwerin Medical CenterDepartment of Hematology and Oncology, Schwerin Medical CenterDepartment of Respiratory Medicine, Schwerin Medical CenterDepartment of Hematology and Oncology, Schwerin Medical CenterAlpha-fetoprotein (AFP) is a tumor marker routinely used for the diagnosis and follow-up of malignant neoplasms. We report a case of extremely high serum levels of AFP associated with benign lesions of the liver and of the lungs with a spontaneous and gradual drop to normal values in the 9-month follow-up without any form of treatment. As a result a high serum level of AFP does not necessarily indicate a malignant tumor and every patient presenting with such finding must be thoroughly examined before making a definitive diagnosis.http://www.pagepress.org/journals/index.php/gi/article/view/6399tumor markers, liver, FNH
collection DOAJ
language English
format Article
sources DOAJ
author Lorenzo Cirri
Farouk Dahmash
Christian Marin
Wolfram Grüning
Ahmet H. Elmaagacli
spellingShingle Lorenzo Cirri
Farouk Dahmash
Christian Marin
Wolfram Grüning
Ahmet H. Elmaagacli
Exaggerated serum levels of alpha-fetoprotein in focal nodular hyperplasia of the liver
Gastroenterology Insights
tumor markers, liver, FNH
author_facet Lorenzo Cirri
Farouk Dahmash
Christian Marin
Wolfram Grüning
Ahmet H. Elmaagacli
author_sort Lorenzo Cirri
title Exaggerated serum levels of alpha-fetoprotein in focal nodular hyperplasia of the liver
title_short Exaggerated serum levels of alpha-fetoprotein in focal nodular hyperplasia of the liver
title_full Exaggerated serum levels of alpha-fetoprotein in focal nodular hyperplasia of the liver
title_fullStr Exaggerated serum levels of alpha-fetoprotein in focal nodular hyperplasia of the liver
title_full_unstemmed Exaggerated serum levels of alpha-fetoprotein in focal nodular hyperplasia of the liver
title_sort exaggerated serum levels of alpha-fetoprotein in focal nodular hyperplasia of the liver
publisher MDPI AG
series Gastroenterology Insights
issn 2036-7414
2036-7422
publishDate 2016-08-01
description Alpha-fetoprotein (AFP) is a tumor marker routinely used for the diagnosis and follow-up of malignant neoplasms. We report a case of extremely high serum levels of AFP associated with benign lesions of the liver and of the lungs with a spontaneous and gradual drop to normal values in the 9-month follow-up without any form of treatment. As a result a high serum level of AFP does not necessarily indicate a malignant tumor and every patient presenting with such finding must be thoroughly examined before making a definitive diagnosis.
topic tumor markers, liver, FNH
url http://www.pagepress.org/journals/index.php/gi/article/view/6399
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AT wolframgruning exaggeratedserumlevelsofalphafetoproteininfocalnodularhyperplasiaoftheliver
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