Increasing MuSK Activity Delays Denervation and Improves Motor Function in ALS Mice
Amyotrophic lateral sclerosis (ALS) is a devastating disease that progresses from detachment of motor nerve terminals to complete muscle paralysis and lethal respiratory failure within 5 years of diagnosis. Genetic studies have linked mutations in several genes to ALS, and mice bearing mutations in...
Main Authors: | María J. Pérez-García, Steven J. Burden |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2012-09-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S221112471200229X |
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