In vitro and in vivo silencing of plasmodial dhs and eIf-5a genes in a putative, non-canonical RNAi-related pathway
<p>Abstract</p> <p>Background</p> <p>Deoxyhypusine synthase (DHS) catalyzes the first step in hypusine biosynthesis of eukaryotic initiation factor 5A (eIF-5A) in <it>Plasmodium falciparum</it>. Target evaluation of parasitic DHS has recently been performed...
Main Authors: | Schwentke Andreas, Krepstakies Marcel, Mueller Ann-Kristin, Hammerschmidt-Kamper Christiane, Motaal Basma A, Bernhard Tina, Hauber Joachim, Kaiser Annette |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-06-01
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Series: | BMC Microbiology |
Online Access: | http://www.biomedcentral.com/1471-2180/12/107 |
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