Onchocerca volvulus bivalent subunit vaccine induces protective immunity in genetically diverse collaborative cross recombinant inbred intercross mice
Abstract This study tests the hypothesis that an Onchocerca volvulus vaccine, consisting of two recombinant antigens (Ov-103 and Ov-RAL-2) formulated with the combination-adjuvant Advax-2, can induce protective immunity in genetically diverse Collaborative Cross recombinant inbred intercross mice (C...
Main Authors: | Nathan M. Ryan, Jessica A. Hess, Fernando Pardo-Manuel de Villena, Benjamin E. Leiby, Ayako Shimada, Lei Yu, Amir Yarmahmoodi, Nikolai Petrovsky, Bin Zhan, Maria Elena Bottazzi, Benjamin L. Makepeace, Sara Lustigman, David Abraham |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-01-01
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Series: | npj Vaccines |
Online Access: | https://doi.org/10.1038/s41541-020-00276-2 |
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