Serum levels of inhibin B in adolescents after varicocelelectomy: A long term follow up
To study the impact on adult’s fertility of serum inhibin B levels in adolescent patients with idiopathic varicocele after minimally invasive surgical correction and to compare fluctuation of pituitary-testis hormonal values and testicular volumes. Materials and Methods: A case-control study was car...
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De Gruyter
2016-01-01
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Online Access: | https://doi.org/10.1515/med-2016-0039 |
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doaj-81be9c4ebf0044e18ac63d5666db66252021-10-02T17:52:39ZengDe GruyterOpen Medicine2391-54632016-01-0111120420610.1515/med-2016-0039med-2016-0039Serum levels of inhibin B in adolescents after varicocelelectomy: A long term follow upMolinaro Francesco0Cerchia Elisa1Garzi Alfredo2Severi Francesco Maria3Angotti Rossella4Petraglia Felice5Messina Mario6Division of Pediatric Surgery, Department of Medical, Surgical and Neurological Sciences, University of Siena, ItalyDivision of Pediatric Surgery, Department of Medical, Surgical and Neurological Sciences, University of Siena, ItalyDepartment of Medicine and Surgery, Pediatric Surgery, Piazza Sergardi, 16, 52044 Cortona (AR) ItalyObstetrics and Gynecology, Department of Molecular and Developmental Medicine, University of Siena, ItalyDivision of Pediatric Surgery, Department of Medical, Surgical and Neurological Sciences, University of Siena, ItalyObstetrics and Gynecology, Department of Molecular and Developmental Medicine, University of Siena, ItalyDivision of Pediatric Surgery, Department of Medical, Surgical and Neurological Sciences, University of Siena, ItalyTo study the impact on adult’s fertility of serum inhibin B levels in adolescent patients with idiopathic varicocele after minimally invasive surgical correction and to compare fluctuation of pituitary-testis hormonal values and testicular volumes. Materials and Methods: A case-control study was carried out on a group adolescent patients (n=60) affected by idiopathic left varicocele (group V) and compared with control adolescents (n=40) in the Paediatric Surgery Section of Siena (from June 1993 till September 2013). Inhibin B levels and testicular volume before (T0) and after at 6 and 12 months from surgery (T1 and T2) were evaluated. Results: A positive correlation between testicular growth at T1 and T2 (P<0.001) was found. Linear regression analysis showed a positive correlation between inhibin B levels and testicular volume (expressed as the sum of the right and left values) (P<0.0001). Conclusions: Inhibin B levels are a valid marker for studying the effects of varicocele on the testicular function and confirm the necessity of early surgical correction for preventing the trophic testicular damage and male infertility.https://doi.org/10.1515/med-2016-0039lung sparing surgeryintralobar pulmonary sequestrationpediatric thoracic surgery |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Molinaro Francesco Cerchia Elisa Garzi Alfredo Severi Francesco Maria Angotti Rossella Petraglia Felice Messina Mario |
spellingShingle |
Molinaro Francesco Cerchia Elisa Garzi Alfredo Severi Francesco Maria Angotti Rossella Petraglia Felice Messina Mario Serum levels of inhibin B in adolescents after varicocelelectomy: A long term follow up Open Medicine lung sparing surgery intralobar pulmonary sequestration pediatric thoracic surgery |
author_facet |
Molinaro Francesco Cerchia Elisa Garzi Alfredo Severi Francesco Maria Angotti Rossella Petraglia Felice Messina Mario |
author_sort |
Molinaro Francesco |
title |
Serum levels of inhibin B in adolescents after varicocelelectomy: A long term follow up |
title_short |
Serum levels of inhibin B in adolescents after varicocelelectomy: A long term follow up |
title_full |
Serum levels of inhibin B in adolescents after varicocelelectomy: A long term follow up |
title_fullStr |
Serum levels of inhibin B in adolescents after varicocelelectomy: A long term follow up |
title_full_unstemmed |
Serum levels of inhibin B in adolescents after varicocelelectomy: A long term follow up |
title_sort |
serum levels of inhibin b in adolescents after varicocelelectomy: a long term follow up |
publisher |
De Gruyter |
series |
Open Medicine |
issn |
2391-5463 |
publishDate |
2016-01-01 |
description |
To study the impact on adult’s fertility of serum inhibin B levels in adolescent patients with idiopathic varicocele after minimally invasive surgical correction and to compare fluctuation of pituitary-testis hormonal values and testicular volumes. Materials and Methods: A case-control study was carried out on a group adolescent patients (n=60) affected by idiopathic left varicocele (group V) and compared with control adolescents (n=40) in the Paediatric Surgery Section of Siena (from June 1993 till September 2013). Inhibin B levels and testicular volume before (T0) and after at 6 and 12 months from surgery (T1 and T2) were evaluated. Results: A positive correlation between testicular growth at T1 and T2 (P<0.001) was found. Linear regression analysis showed a positive correlation between inhibin B levels and testicular volume (expressed as the sum of the right and left values) (P<0.0001). Conclusions: Inhibin B levels are a valid marker for studying the effects of varicocele on the testicular function and confirm the necessity of early surgical correction for preventing the trophic testicular damage and male infertility. |
topic |
lung sparing surgery intralobar pulmonary sequestration pediatric thoracic surgery |
url |
https://doi.org/10.1515/med-2016-0039 |
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