Effects of Single Nucleotide Polymorphisms in Human KCNMA1 on BK Current Properties

Effects of Single Nucleotide Polymorphisms in Human KCNMA1 on BK Current Properties

BK Ca2+-activated K+ channels are important regulators of membrane excitability. Multiple regulatory mechanisms tailor BK current properties across tissues, such as alternative splicing, posttranslational modifications, and auxiliary subunits. Another potential mechanism for modulating BK channel ac...

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Bibliographic Details
Main Authors: Amber E. Plante, Michael H. Lai, Jessica Lu, Andrea L. Meredith
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Molecular Neuroscience
Subjects:
BK channel
KCa1.1
calcium-activated potassium channel
KCNMA1
potassium channel
MaxiK
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00285/full

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https://www.frontiersin.org/article/10.3389/fnmol.2019.00285/full

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