Mild therapeutic hypothermia protects against cerebral ischemia/reperfusion injury by inhibiting miR-15b expression in rats

Mild therapeutic hypothermia protects against cerebral ischemia/reperfusion injury by inhibiting miR-15b expression in rats

OBJECTIVE: Mild hypothermia has a protective effect on ischemic stroke, but the mechanisms remain elusive. Here, we investigated microRNA (miRNA) profiles and the specific role of miRNAs in ischemic stroke treated with mild hypothermia. MATERIALS AND METHODS: Male adult Sprague Dawley rats were subj...

Full description

Bibliographic Details
Main Authors: Xiangrong Liu, Di Wu, Shaohong Wen, Shunying Zhao, Ao Xia, Fang Li, Xunming Ji
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Brain Circulation
Subjects:
ADP ribosylation factor-like 2
cerebral ischemia
hypothermia
microRNA
neuroprotection
Online Access:http://www.braincirculation.org/article.asp?issn=2394-8108;year=2017;volume=3;issue=4;spage=219;epage=226;aulast=Liu

Similar Items

Similar Items