The Role of Secretory Pathways in <i>Candida albicans</i> Pathogenesis

The Role of Secretory Pathways in <i>Candida albicans</i> Pathogenesis

<i>Candida albicans </i>is a fungus that is a commensal organism and a member of the normal human microbiota. It has the ability to transition into an opportunistic invasive pathogen. Attributes that support pathogenesis include secretion of virulence-associated proteins, hyphal formatio...

Full description

Bibliographic Details
Main Authors: Christiane Rollenhagen, Sahil Mamtani, Dakota Ma, Reva Dixit, Susan Eszterhas, Samuel A. Lee
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Journal of Fungi
Subjects:
<i>candida albicans</i>
biofilm
filamentation
pathogenesis
secretion
trafficking
virulence
Online Access:https://www.mdpi.com/2309-608X/6/1/26
Description
Summary:<i>Candida albicans </i>is a fungus that is a commensal organism and a member of the normal human microbiota. It has the ability to transition into an opportunistic invasive pathogen. Attributes that support pathogenesis include secretion of virulence-associated proteins, hyphal formation, and biofilm formation. These processes are supported by secretion, as defined in the broad context of membrane trafficking. In this review, we examine the role of secretory pathways in <i>Candida</i> virulence, with a focus on the model opportunistic fungal pathogen, <i>Candida albicans</i>.
ISSN:2309-608X

Similar Items